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IL-4 抗体 (Middle Region)

IL4 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2785656
发货至: 中国
  • 抗原 See all IL-4 (IL4) 抗体
    IL-4 (IL4) (Interleukin 4 (IL4))
    抗原表位
    • 18
    • 10
    • 6
    • 6
    • 5
    • 5
    • 5
    • 4
    • 3
    • 2
    • 2
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    • 1
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    • 1
    • 1
    • 1
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    • 1
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    Middle Region
    适用
    • 136
    • 57
    • 22
    • 14
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    • 8
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    • 5
    • 5
    • 4
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    • 2
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    • 1
    宿主
    • 110
    • 59
    • 56
    • 7
    • 3
    • 2
    克隆类型
    • 127
    • 107
    • 1
    多克隆
    标记
    • 139
    • 33
    • 16
    • 13
    • 10
    • 8
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
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    This IL-4 antibody is un-conjugated
    应用范围
    • 119
    • 110
    • 70
    • 61
    • 25
    • 20
    • 19
    • 16
    • 13
    • 13
    • 12
    • 11
    • 9
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    • 1
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    • 1
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    • 1
    Western Blotting (WB)
    序列
    TVLRQFYSHH EKDTRCLGAT AQQFHRHKQL IRFLKRLDRN LWGLAGLNSC
    预测反应
    Human: 100%
    产品特性
    This is a rabbit polyclonal antibody against IL4. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the middle region of human IL4
    Top Product
    Discover our top product IL4 Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 153 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    IL-4 (IL4) (Interleukin 4 (IL4))
    别名
    IL4 (IL4 产品)
    别名
    IL4 antibody, IL-4 antibody, BCGF-1 antibody, BCGF1 antibody, BSF-1 antibody, BSF1 antibody, Il-4 antibody, Il4e12 antibody, IL2 antibody, interleukin 4 antibody, IL4 antibody, Il4 antibody
    背景
    IL4 is a pleiotropic cytokine produced by activated T cells. This cytokine is a ligand for interleukin 4 receptor. The interleukin 4 receptor also binds to IL13, which may contribute to many overlapping functions of this cytokine and IL13. STAT6, a signal transducer and activator of transcription, has been shown to play a central role in mediating the immune regulatory signal of this cytokine. The protein encoded by this gene is a pleiotropic cytokine produced by activated T cells. This cytokine is a ligand for interleukin 4 receptor. The interleukin 4 receptor also binds to IL13, which may contribute to many overlapping functions of this cytokine and IL13. STAT6, a signal transducer and activator of transcription, has been shown to play a central role in mediating the immune regulatory signal of this cytokine. This gene, IL3, IL5, IL13, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL13. This gene, IL13 and IL5 are found to be regulated coordinately by several long-range regulatory elements in an over 120 kilobase range on the chromosome. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.
    Alias Symbols: BSF1, IL-4, MGC79402, BCGF1, BSF-1, BCGF-1
    Protein Interaction Partner: IL13, IL4, PIK3CD, IL2RG, IL13RA2, CD53, IL4R, A2M,
    Protein Size: 153
    分子量
    15 kDa
    基因ID
    3565
    NCBI登录号
    NM_000589, NP_000580
    UniProt
    P05112
    途径
    JAK/STAT Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Proton Transport, Activated T Cell Proliferation
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