(1 reference)-
- 抗原 See all MLF1 抗体
- MLF1 (Myeloid Leukemia Factor 1 (MLF1))
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抗原表位
- N-Term
- 适用
- 人, 小鼠, 大鼠, 兔
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This MLF1 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- GRDLLSISDG RGRAHNRRGH NDGEDSLTHT DVSSFQTMDQ MVSNMRNYMQ
- 预测反应
- Human: 100%, Mouse: 79%, Rabbit: 90%, Rat: 79%
- 产品特性
- This is a rabbit polyclonal antibody against MLF1. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human MLF1
- Top Product
- Discover our top product MLF1 Primary Antibody
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anti-Myeloid Leukemia Factor 1 (MLF1) antibody
MLF1 适用: 人 WB, IHC, FACS, IF, IHC (p) 宿主: 小鼠 Monoclonal 3A3 unconjugated
anti-Myeloid Leukemia Factor 1 (MLF1) (pThr78) antibodyMLF1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Myeloid Leukemia Factor 1 (MLF1) (AA 215-244), (C-Term) antibodyMLF1 适用: 人, 小鼠 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB18643 unconjugated
anti-Myeloid Leukemia Factor 1 (MLF1) antibodyMLF1 适用: 小鼠, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Myeloid Leukemia Factor 1 (MLF1) (AA 1-268) antibodyMLF1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Myeloid Leukemia Factor 1 (MLF1) (AA 1-268) antibodyMLF1 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Myeloid Leukemia Factor 1 (MLF1) (AA 1-268) antibodyMLF1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Myeloid Leukemia Factor 1 (MLF1) (AA 1-268) antibodyMLF1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Myeloid Leukemia Factor 1 (MLF1) (AA 91-126) antibodyMLF1 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB51172 unconjugated
anti-Myeloid Leukemia Factor 1 (MLF1) antibodyMLF1 适用: 人, 小鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 268 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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: "Non-pathogenic protein aggregates in skeletal muscle in MLF1 transgenic mice." in: Journal of the neurological sciences, Vol. 264, Issue 1-2, pp. 77-86, (2007) (PubMed).
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: "Non-pathogenic protein aggregates in skeletal muscle in MLF1 transgenic mice." in: Journal of the neurological sciences, Vol. 264, Issue 1-2, pp. 77-86, (2007) (PubMed).
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- 抗原
- MLF1 (Myeloid Leukemia Factor 1 (MLF1))
- 别名
- MLF1 (MLF1 产品)
- 别名
- MLF1 antibody, HLS7 antibody, myeloid leukemia factor 1 antibody, myeloid leukemia factor 1 L homeolog antibody, MLF1 antibody, mlf1.L antibody, mlf1 antibody, Mlf1 antibody
- 背景
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MLF1 is involved in lineage commitment of primary hemopoietic progenitors by restricting erythroid formation and enhancing myeloid formation. It interferes with erythopoietin-induced erythroid terminal differentiation by preventing cells from exiting the cell cycle through suppression of CDKN1B/p27Kip1 levels. MLF1 suppresses RFWD2/COP1 activity via CSN3 which activates p53 and induces cell cycle arrest.It binds DNA and affects the expression of a number of genes so may function as a transcription factor in the nucleus.
Alias Symbols: -
Protein Interaction Partner: CENPU, COPS3, UBC, NRBP1, YWHAZ, GRIK5, MAGEA11,
Protein Size: 268 - 分子量
- 29 kDa
- 基因ID
- 4291
- NCBI登录号
- NM_022443, NP_071888
- UniProt
- P58340
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