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PRKAA1 抗体 (Middle Region)

PRKAA1 适用: 人, 小鼠, 大鼠, 犬, Cow, 兔, 马, 豚鼠, 斑马鱼, 绵羊 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2785500
发货至: 中国
  • 抗原 See all PRKAA1 抗体
    PRKAA1 (Protein Kinase, AMP-Activated, alpha 1 Catalytic Subunit (PRKAA1))
    抗原表位
    • 30
    • 17
    • 16
    • 15
    • 8
    • 8
    • 7
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    Middle Region
    适用
    • 155
    • 131
    • 88
    • 26
    • 10
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    • 8
    • 7
    • 7
    • 7
    • 4
    • 4
    • 4
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    人, 小鼠, 大鼠, 犬, Cow, 兔, 马, 豚鼠, 斑马鱼, 绵羊
    宿主
    • 155
    • 17
    • 1
    克隆类型
    • 143
    • 30
    多克隆
    标记
    • 85
    • 10
    • 9
    • 9
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 4
    • 4
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    • 4
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    • 1
    • 1
    This PRKAA1 antibody is un-conjugated
    应用范围
    • 136
    • 58
    • 45
    • 41
    • 40
    • 40
    • 34
    • 20
    • 13
    • 12
    • 11
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB)
    序列
    SVISLLKHML QVDPMKRATI KDIREHEWFK QDLPKYLFPE DPSYSSTMID
    预测反应
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 93%, Zebrafish: 100%
    产品特性
    This is a rabbit polyclonal antibody against PRKAA1. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the middle region of human PRKAA1
    Top Product
    Discover our top product PRKAA1 Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 559 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    PRKAA1 (Protein Kinase, AMP-Activated, alpha 1 Catalytic Subunit (PRKAA1))
    别名
    PRKAA1 (PRKAA1 产品)
    别名
    AMPK antibody, AMPKa1 antibody, cb116 antibody, im:7154392 antibody, sb:cb130 antibody, wu:fa94c10 antibody, AMPK1 antibody, AMPKalpha1 antibody, AI194361 antibody, AI450832 antibody, AL024255 antibody, C130083N04Rik antibody, ampk antibody, ampka1 antibody, PRKAA1 antibody, protein kinase AMP-activated catalytic subunit alpha 1 antibody, protein kinase, AMP-activated, alpha 1 catalytic subunit antibody, protein kinase, AMP-activated, alpha 1 catalytic subunit L homeolog antibody, PRKAA1 antibody, prkaa1 antibody, Prkaa1 antibody, prkaa1.L antibody
    背景
    PRKAA1 belongs to the ser/thr protein kinase family. It is the catalytic subunit of the 5'-prime-AMP-activated protein kinase (AMPK). AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP/ATP ratio. AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. The protein encoded by this gene belongs to the ser/thr protein kinase family. It is the catalytic subunit of the 5'-prime-AMP-activated protein kinase (AMPK). AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP/ATP ratio. AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. Alternatively spliced transcript variants encoding distinct isoforms have been observed.
    Alias Symbols: AMPK, AMPKa1, MGC33776, MGC57364
    Protein Interaction Partner: PRKAG1, PRKAB2, PRKAB1, GOLGA2, PHC2, CTBP1, CDX4, AES, Trp53, INO80E, RFX6, TRIM27, KRT40, SSX2IP, PNMA5, UBXN11, RIMBP3, L3MBTL3, TSC22D4, VPS37B, HMBOX1, HOMEZ, THAP1, ROPN1, RAD54B, MTUS2, IKZF3, RBPMS, ABI2, ZBED1, BHLHE40, TRIP6, STK11, VPS52, PPARG
    Protein Size: 559
    分子量
    63 kDa
    基因ID
    5562
    NCBI登录号
    NM_006251, NP_006242
    UniProt
    Q13131
    途径
    AMPK Signaling, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process, Warburg Effect
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