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Crossover junction endonuclease EME1 (EME1) (Middle Region) 抗体

EME1 适用: 人, 小鼠, 大鼠, Pig, Cow, 犬, 豚鼠, 马, 兔 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2785184
发货至: 中国
  • 抗原 See all Crossover junction endonuclease EME1 (EME1) 抗体
    Crossover junction endonuclease EME1 (EME1)
    抗原表位
    • 7
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Middle Region
    适用
    • 20
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    人, 小鼠, 大鼠, Pig, Cow, 犬, 豚鼠, 马, 兔
    宿主
    • 17
    • 4
    克隆类型
    • 19
    • 2
    多克隆
    标记
    • 17
    • 2
    • 1
    • 1
    非结合性
    应用范围
    • 16
    • 8
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    序列
    AYPSPQLLVQ AYQQCFSDKE RQNLLADIQV RRGEGVTSTS RRIGPELSRR
    预测反应
    Cow: 93%, Dog: 100%, Guinea Pig: 79%, Horse: 93%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 93%
    产品特性
    This is a rabbit polyclonal antibody against EME1. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the middle region of human EME1
    Top Product
    Discover our top product EME1 Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 570 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    Crossover junction endonuclease EME1 (EME1)
    别名
    EME1 (EME1 产品)
    别名
    6820428D13 antibody, essential meiotic structure-specific endonuclease 1 antibody, Eme1 antibody
    背景
    EME1 interacts with MUS81 to form a DNA structure-specific endonuclease with substrate preference for branched DNA structures with a 5'-end at the branch nick. Typical substrates include 3'-flap structures, replication forks and nicked Holliday junctions. EME1 may be required in mitosis for the processing of stalled or collapsed replication forks.EME1 and MUS81 (MIM 606591) form an endonuclease complex that cleaves branched DNA structures, especially those arising during stalled DNA replication (Abraham et al., 2003 [PubMed 14609959]).[supplied by OMIM].
    Alias Symbols: FLJ31364, MMS4L, SLX2A
    Protein Interaction Partner: vpr, MUS81, APP, SLX1A, EME1, SLX4, SUMO2, SLX1B,
    Protein Size: 570
    分子量
    63 kDa
    基因ID
    146956
    NCBI登录号
    NM_152463, NP_689676
    UniProt
    Q96AY2
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