RDH12 抗体 (Middle Region)
(1 reference)-
- 抗原 See all RDH12 抗体
- RDH12 (Retinol Dehydrogenase 12 (All-Trans/9-Cis/11-Cis) (RDH12))
-
抗原表位
- Middle Region
-
适用
- 人, Pig, 大鼠, 犬
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This RDH12 antibody is un-conjugated
-
应用范围
- Western Blotting (WB)
- 序列
- HIGKIPFHDL QSEKRYSRGF AYCHSKLANV LFTRELAKRL QGTGVTTYAV
- 预测反应
- Dog: 93%, Human: 100%, Pig: 79%, Rat: 79%
- 产品特性
- This is a rabbit polyclonal antibody against RDH12. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human RDH12
- Top Product
- Discover our top product RDH12 Primary Antibody
-
anti-Retinol Dehydrogenase 12 (All-Trans/9-Cis/11-Cis) (RDH12) (AA 1-316) antibody
RDH12 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Retinol Dehydrogenase 12 (All-Trans/9-Cis/11-Cis) (RDH12) (AA 217-316) antibodyRDH12 适用: 人 ELISA, WB, IF 宿主: 小鼠 Monoclonal 1E11 unconjugated
anti-Retinol Dehydrogenase 12 (All-Trans/9-Cis/11-Cis) (RDH12) (AA 182-316) antibodyRDH12 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Retinol Dehydrogenase 12 (All-Trans/9-Cis/11-Cis) (RDH12) (AA 1-316) antibodyRDH12 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Retinol Dehydrogenase 12 (All-Trans/9-Cis/11-Cis) (RDH12) (AA 1-316) antibodyRDH12 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Retinol Dehydrogenase 12 (All-Trans/9-Cis/11-Cis) (RDH12) (AA 179-228) antibodyRDH12 适用: 人, Pig, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Retinol Dehydrogenase 12 (All-Trans/9-Cis/11-Cis) (RDH12) (AA 215-264) antibodyRDH12 适用: 人, Pig, 豚鼠, 兔, Cow WB 宿主: 兔 Polyclonal unconjugated
-
- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
-
Antigen size: 316 AA
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
-
: "Novel RDH12 mutations associated with Leber congenital amaurosis and cone-rod dystrophy: biochemical and clinical evaluations." in: Vision research, Vol. 47, Issue 15, pp. 2055-66, (2007) (PubMed).
-
: "Novel RDH12 mutations associated with Leber congenital amaurosis and cone-rod dystrophy: biochemical and clinical evaluations." in: Vision research, Vol. 47, Issue 15, pp. 2055-66, (2007) (PubMed).
-
- 抗原
- RDH12 (Retinol Dehydrogenase 12 (All-Trans/9-Cis/11-Cis) (RDH12))
- 别名
- RDH12 (RDH12 产品)
- 别名
- wu:fj43a10 antibody, zgc:92430 antibody, A930033N07Rik antibody, LCA13 antibody, LCA3 antibody, RP53 antibody, SDR7C2 antibody, DSSDR2 antibody, retinol dehydrogenase 12 (all-trans/9-cis/11-cis) antibody, retinol dehydrogenase 12 antibody, Retinol dehydrogenase 12 antibody, RDH12 antibody, rdh12 antibody, MAV_1968 antibody, CC1G_02720 antibody, Bm1_36660 antibody, PTRG_03574 antibody, PTRG_05326 antibody, PTRG_08067 antibody, LOC100282710 antibody, LOC100285880 antibody, LOC100226769 antibody, Rdh12 antibody
- 背景
-
RDH12 is an NADPH-dependent retinal reductase whose highest activity is toward 9-cis and all-trans-retinol. RDH12 also plays a role in the metabolism of short-chain aldehydes but does not exhibit steroid dehydrogenase activity. Defects in this gene are a cause of Leber congenital amaurosis type 3 (LCA3).The protein encoded by this gene is an NADPH-dependent retinal reductase whose highest activity is toward 9-cis and all-trans-retinol. The encoded enzyme also plays a role in the metabolism of short-chain aldehydes but does not exhibit steroid dehydrogenase activity. Defects in this gene are a cause of Leber congenital amaurosis type 3 (LCA3).
Alias Symbols: FLJ30273, LCA3, LCA13, SDR7C2
Protein Interaction Partner: RBPMS, UBC, ANXA8L1, MAP1LC3A, BUB1,
Protein Size: 316 - 分子量
- 35 kDa
- 基因ID
- 145226
- NCBI登录号
- NM_152443, NP_689656
- UniProt
- Q96NR8
-
