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DCK 抗体 (Middle Region)

DCK 适用: 人, 小鼠, 大鼠, 兔, 犬, Cow, 豚鼠, 马, Pig, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2784622
发货至: 中国
  • 抗原 See all DCK 抗体
    DCK (Deoxycytidine Kinase (DCK))
    抗原表位
    • 8
    • 5
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    适用
    • 46
    • 26
    • 13
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠, 兔, 犬, Cow, 豚鼠, 马, Pig, 斑马鱼
    宿主
    • 38
    • 8
    • 3
    克隆类型
    • 43
    • 6
    多克隆
    标记
    • 31
    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This DCK antibody is un-conjugated
    应用范围
    • 34
    • 21
    • 20
    • 20
    • 17
    • 11
    • 9
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    序列
    ATPETCLHRI YLRGRNEEQG IPLEYLEKLH YKHESWLLHR TLKTNFDYLQ
    预测反应
    Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 93%, Zebrafish: 93%
    产品特性
    This is a rabbit polyclonal antibody against DCK. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the middle region of human DCK
    Top Product
    Discover our top product DCK Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 260 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Bieghs, Caers, De Bruyne, Van Valckenborgh, Higginbotham, Vanderkerken, Menu: "The effects of forodesine in murine and human multiple myeloma cells." in: Advances in hematology, Vol. 2010, pp. 131895, (2010) (PubMed).

  • 抗原
    DCK (Deoxycytidine Kinase (DCK))
    别名
    DCK (DCK 产品)
    别名
    dck antibody, DCK antibody, wu:fc15f06 antibody, zgc:101771 antibody, dck1 antibody, deoxycytidine kinase antibody, deoxycytidine kinase, gene 2 L homeolog antibody, deoxycytidine kinase, gene 2 antibody, Deoxycytidine kinase antibody, deoxycytidine kinase, gene 1 L homeolog antibody, DCK antibody, dck antibody, dck.2.L antibody, dck.2 antibody, Dck antibody, FPV059 antibody, FPV151 antibody, dck.1.L antibody
    背景
    Deoxycytidine kinase (DCK) is required for the phosphorylation of several deoxyribonucleosides and their nucleoside analogs. Deficiency of DCK is associated with resistance to antiviral and anticancer chemotherapeutic agents. Conversely, increased deoxycytidine kinase activity is associated with increased activation of these compounds to cytotoxic nucleoside triphosphate derivatives. DCK is clinically important because of its relationship to drug resistance and sensitivity.Deoxycytidine kinase (DCK) is required for the phosphorylation of several deoxyribonucleosides and their nucleoside analogs. Deficiency of DCK is associated with resistance to antiviral and anticancer chemotherapeutic agents. Conversely, increased deoxycytidine kinase activity is associated with increased activation of these compounds to cytotoxic nucleoside triphosphate derivatives. DCK is clinically important because of its relationship to drug resistance and sensitivity. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    Alias Symbols: MGC117410, MGC138632
    Protein Interaction Partner: UBC, EFHD2, CHRAC1, CHMP4A, CBX3, TYMS, THOP1, TALDO1, RBBP7, RANBP1, PTMS, IDH1, HSPE1, ADSS, TFEC, ELAVL1, RXRG, DCK, MED19, GOLM1, DDX19B,
    Protein Size: 260
    分子量
    30 kDa
    基因ID
    1633
    NCBI登录号
    NM_000788, NP_000779
    UniProt
    P27707
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