WNT3 抗体 (Middle Region)
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- 抗原 See all WNT3 抗体
- WNT3 (Wingless-Type MMTV Integration Site Family, Member 3 (WNT3))
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抗原表位
- Middle Region
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适用
- 人, 小鼠, 大鼠, 犬, Cow, 马, 斑马鱼, 豚鼠, 兔
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This WNT3 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- SHHKGPPGEG WKWGGCSEDA DFGVLVSREF ADARENRPDA RSAMNKHNNE
- 预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%
- 产品特性
- This is a rabbit polyclonal antibody against WNT3. It was validated on Western Blot.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human WNT3
- Top Product
- Discover our top product WNT3 Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 355 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- WNT3 (Wingless-Type MMTV Integration Site Family, Member 3 (WNT3))
- 别名
- WNT3 (WNT3 产品)
- 别名
- INT4 antibody, Ci-Wnt3 antibody, WNT3 antibody, int4 antibody, Xwnt3 antibody, wnt-3 antibody, wnt3l antibody, Xwnt-3 antibody, wnt3 antibody, Int-4 antibody, Wnt-3 antibody, wnt3-A antibody, Wnt family member 3 antibody, wingless-type MMTV integration site family, member 3 antibody, proto-oncogene Wnt-3 antibody, wingless-type MMTV integration site family member 3 antibody, Wnt family member 3A antibody, wingless-type MMTV integration site family member 3 L homeolog antibody, WNT3 antibody, Wnt3 antibody, wnt3 antibody, LOC468297 antibody, WNT3A antibody, wnt3.L antibody
- 背景
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The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It encodes a protein which shows 98 % amino acid identity to mouse Wnt3 protein, and 84 % to human WNT3A protein, another WNT gene product. The mouse studies show the requirement of Wnt3 in primary axis formation in the mouse. Studies of the gene expression suggest that this gene may play a key role in some cases of human breast, rectal, lung, and gastric cancer through activation of the WNT-beta-catenin-TCF signaling pathway. This gene is clustered with WNT15, another family member, in the chromosome 17q21 region.
Alias Symbols: INT4, MGC131950, MGC138321, MGC138323
Protein Interaction Partner: FZD1,
Protein Size: 355 - 分子量
- 37 kDa
- 基因ID
- 7473
- NCBI登录号
- NM_030753, NP_110380
- UniProt
- P56703
- 途径
- WNT signaling, Regulation of Cell Size
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