HSD3B7 抗体 (Middle Region)
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- 抗原 See all HSD3B7 抗体
- HSD3B7 (Hydroxy-delta-5-Steroid Dehydrogenase, 3 beta- and Steroid delta-Isomerase 7 (HSD3B7))
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抗原表位
- Middle Region
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适用
- 人, 大鼠, 小鼠, Cow, 马, 兔, 犬, 豚鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This HSD3B7 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- QGTRNVIEAC VQTGTRFLVY TSSMEVVGPN TKGHPFYRGN EDTPYEAVHR
- 预测反应
- Cow: 86%, Dog: 93%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
- 产品特性
- This is a rabbit polyclonal antibody against HSD3B7. It was validated on Western Blot.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human HSD3B7
- Top Product
- Discover our top product HSD3B7 Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 369 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- HSD3B7 (Hydroxy-delta-5-Steroid Dehydrogenase, 3 beta- and Steroid delta-Isomerase 7 (HSD3B7))
- 别名
- HSD3B7 (HSD3B7 产品)
- 别名
- CBAS1 antibody, PFIC4 antibody, SDR11E3 antibody, AI195443 antibody, BB098564 antibody, Cca2 antibody, hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7 antibody, HSD3B7 antibody, Hsd3b7 antibody
- 背景
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This gene encodes an enzyme which is involved in the initial stages of the synthesis of bile acids from cholesterol and a member of the short-chain dehydrogenase/reductase superfamily. The encoded protein is a membrane-associated endoplasmic reticulum protein which is active against 7-alpha hydrosylated sterol substrates. Mutations in this gene are associated with a congenital bile acid synthesis defect which leads to neonatal cholestasis, a form of progressive liver disease. Multiple transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: PFIC4, CBAS1, SDR11E3
Protein Interaction Partner: NOTCH2NL, KRTAP10-3, KRTAP10-8, KRTAP10-1, KRTAP10-9, KRTAP4-2, SPRY2, UBC, KRTAP10-7, DAPP1, PYGL, ICAM1, Hoxa1,
Protein Size: 369 - 分子量
- 41 kDa
- 基因ID
- 80270
- NCBI登录号
- NM_025193, NP_079469
- UniProt
- Q9H2F3
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