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PFN1 抗体 (N-Term)

PFN1 适用: 人, 小鼠, 大鼠, Cow, 豚鼠, 马, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2783306
发货至: 中国
  • 抗原 See all PFN1 抗体
    PFN1 (Profilin 1 (PFN1))
    抗原表位
    • 14
    • 8
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    • 55
    • 32
    • 30
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠, Cow, 豚鼠, 马, 斑马鱼
    宿主
    • 62
    • 5
    克隆类型
    • 53
    • 14
    多克隆
    标记
    • 26
    • 8
    • 7
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    This PFN1 antibody is un-conjugated
    应用范围
    • 33
    • 22
    • 14
    • 13
    • 12
    • 11
    • 9
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB)
    序列
    AGWNAYIDNL MADGTCQDAA IVGYKDSPSV WAAVPGKTFV NITPAEVGVL
    预测反应
    Cow: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 91%
    产品特性
    This is a rabbit polyclonal antibody against PFN1. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the N terminal region of human PFN1
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 140 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Witt, Büttner, Jannasch, Matschke, Waldow: "Reversal of myofibroblastic activation by polyunsaturated fatty acids in valvular interstitial cells from aortic valves. Role of RhoA/G-actin/MRTF signalling." in: Journal of molecular and cellular cardiology, Vol. 74, pp. 127-38, (2014) (PubMed).

  • 抗原
    PFN1 (Profilin 1 (PFN1))
    别名
    PFN1 (PFN1 产品)
    别名
    GmPRO1 antibody, GmPRO2 antibody, PRO1 antibody, Profilin-1 antibody, profilin-1 antibody, profilin antibody, MGC130883 antibody, Profilin1 antibody, XProfilin1 antibody, sb:cb813 antibody, wu:fa91a03 antibody, ALS18 antibody, Pfn antibody, F6F22.21 antibody, F6F22_21 antibody, PFN1 antibody, PROFILIN 1 antibody, profilin 1 antibody, profilin antibody, profilin 1 antibody, profilin 1 L homeolog antibody, profilin homolog 1 antibody, Profilin-1 antibody, PRO2 antibody, PFN1 antibody, pfn1.L antibody, pfn1 antibody, Pfn1 antibody, PRF1 antibody, prf1 antibody, pfn-1 antibody
    背景
    PFN1 is a ubiquitous actin monomer-binding protein belonging to the profilin family. It is thought to regulate actin polymerization in response to extracellular signals. Deletion of this gene is associated with Miller-Dieker syndrome.The protein encoded by this gene is a ubiquitous actin monomer-binding protein belonging to the profilin family. It is thought to regulate actin polymerization in response to extracellular signals. Deletion of this gene is associated with Miller-Dieker syndrome. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    Alias Symbols: -
    Protein Interaction Partner: UBC, FUS, STUB1, SUMO1, NEDD8, MDM2, ASB12, ASB2, ASB1, YWHAQ, SRPK1, ESR1, RAD52, RAD51, ACTB, VCAM1, ITGA4, FN1, ATF2, LIG4, SET, ACAA2, LOC440434, MRPL53, SRPRB, CAND1, CUL3, CDK2, ISG15, ELAVL1, AI837181, Akap12, Csnk1e, Mapk13, UCHL5, WIPF2, LRIF1, M
    Protein Size: 140
    分子量
    15 kDa
    基因ID
    5216
    NCBI登录号
    NM_005022, NP_005013
    UniProt
    P07737
    途径
    Regulation of Actin Filament Polymerization, Tube Formation, Maintenance of Protein Location
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