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MGA (C-Term) 抗体

适用: 人, Pig, 兔, 大鼠, Cow, 犬, 马, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2783018
发货至: 中国
  • 抗原
    MGA
    抗原表位
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    人, Pig, 兔, 大鼠, Cow, 犬, 马, 小鼠
    宿主
    • 4
    克隆类型
    • 4
    多克隆
    标记
    • 4
    非结合性
    应用范围
    • 2
    • 1
    • 1
    Western Blotting (WB)
    序列
    ASLQMKRESQ NPDQKDETNS IKREQETKKV LQSEGEAVDP EANVIKQNSG
    预测反应
    Cow: 92%, Dog: 85%, Horse: 92%, Human: 100%, Mouse: 79%, Pig: 92%, Rabbit: 79%, Rat: 79%
    产品特性
    This is a rabbit polyclonal antibody against MGA. It was validated on Western Blot.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the C-terminal region of Human MGA
  • 限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeat freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    MGA
    背景
    MGA functions as a dual-specificity transcription factor, regulating the expression of both MAX-network and T-box family target genes and functions as a repressor or an activator. It binds to 5'-AATTTCACACCTAGGTGTGAAATT-3' core sequence and seems to regulate MYC-MAX target genes. It suppresses transcriptional activation by MYC and inhibits MYC-dependent cell transformation. It function activated by heterodimerization with MAX. This heterodimerization serves the dual function of both generating an E-box-binding heterodimer and simultaneously blocking interaction of a corepressor
    Protein Interaction Partner: SUMO2, SUMO3, EED, RNF2, MAX, SMAD1, LSM8, UBC, CD2BP2, CBX2, PCGF6, RYBP, PCGF3, YAF2, CBX4, CBX3, E2F4, E2F3, E2F1,
    Protein Size: 697
    分子量
    76 kDa
    基因ID
    23269
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