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Lamin B2 抗体 (N-Term)

LMNB2 适用: 人, 小鼠, 大鼠, 马, Cow, 豚鼠, 兔 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2782594
发货至: 中国
  • 抗原 See all Lamin B2 (LMNB2) 抗体
    Lamin B2 (LMNB2)
    抗原表位
    • 15
    • 7
    • 6
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    • 53
    • 39
    • 18
    • 10
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠, 马, Cow, 豚鼠, 兔
    宿主
    • 51
    • 17
    克隆类型
    • 48
    • 20
    多克隆
    标记
    • 37
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This Lamin B2 antibody is un-conjugated
    应用范围
    • 49
    • 15
    • 14
    • 14
    • 13
    • 13
    • 12
    • 8
    • 7
    • 7
    • 7
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    序列
    MATPLPGRAG GPATPLSPTR LSRLQEKEEL RELNDRLAHY IDRVRALELE
    预测反应
    Cow: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 85%, Rat: 92%
    产品特性
    This is a rabbit polyclonal antibody against LMNB2. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the N terminal region of human LMNB2
    Top Product
    Discover our top product LMNB2 Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 600 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Jacinto, Benner, Hetzer: "The nucleoporin Nup153 regulates embryonic stem cell pluripotency through gene silencing." in: Genes & development, Vol. 29, Issue 12, pp. 1224-38, (2015) (PubMed).

    Tsai, Wang, Heidinger, Shumaker, Adam, Goldman, Zheng: "A mitotic lamin B matrix induced by RanGTP required for spindle assembly." in: Science (New York, N.Y.), Vol. 311, Issue 5769, pp. 1887-93, (2006) (PubMed).

  • 抗原
    Lamin B2 (LMNB2)
    别名
    LMNB2 (LMNB2 产品)
    别名
    lmnb2-a antibody, LMNB2 antibody, lmn2 antibody, lamb2 antibody, Lamin-L(II) antibody, LOC100136040 antibody, im:7142331 antibody, lamin antibody, wu:fb94e05 antibody, wu:fb95e12 antibody, wu:fc15d06 antibody, wu:fc49h03 antibody, lamin-b2 antibody, lmnb2 antibody, LAMB2 antibody, LMN2 antibody, RGD1563803 antibody, lamin B2 S homeolog antibody, lamin B2 antibody, lamin B2 L homeolog antibody, lmnb2.S antibody, LMNB2 antibody, lmnb2 antibody, lmnb2.L antibody, Lmnb2 antibody
    背景
    The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. LMNB2 is one of the two B type proteins, B2.The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. This gene encodes one of the two B type proteins, B2. This gene is in a head-to-tail orientation with the gene for the translocase of inner mitochondrial membrane 13 homolog gene.
    Alias Symbols: LAMB2, LMN2, MGC2721
    Protein Interaction Partner: UBC, GPRASP2, SUZ12, EED, RNF2, LMNA, PAN2, VCP, UBD, SIRT7, ELAVL1, SVIL, BANF1, PRKCD, LMNB2, TMPO, XRCC5, ORC2,
    Protein Size: 600
    分子量
    68 kDa
    基因ID
    84823
    NCBI登录号
    NM_032737, NP_116126
    UniProt
    Q03252
    途径
    Apoptosis, Caspase Cascade in Apoptosis
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