HIST1H1C 抗体 (Histone Cluster 1, H1c) (Middle Region)

Details for Product anti-HIST1H1C Antibody No. ABIN2782497, 供应商: Log in to see
抗原
  • HIST1H1C
  • H1.2
  • H1C
  • H1F2
  • H1s-1
  • 0610008C09Rik
  • H1c
  • H1f2
  • H1var1
  • His1a
  • H14
  • H1d
  • H1f4
  • Hist1h1c
  • Hist1h1e
  • histone cluster 1, H1c
  • histone cluster 1, H1.11L (similar to human histone cluster 1, class H1 genes)
  • histone cluster 1, H1d
  • HIST1H1C
  • HIST1H111L
  • Hist1h1c
  • Hist1h1d
抗原表位
Middle Region
11
10
8
7
2
1
1
适用
牛, 犬, 豚鼠, 马, 人, 小鼠, 兔, 大鼠
37
8
8
宿主

37
克隆类型
多克隆
标记
This HIST1H1C antibody is un-conjugated
2
2
2
2
2
2
应用范围
Chromatin Immunoprecipitation (ChIP), Western Blotting (WB)
34
22
10
4
3
3
2
1
选项
Supplier
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免疫原 The immunogen is a synthetic peptide directed towards the middle region of human HIST1H1C
Blocking Peptide Blocking peptide for this product available: ABIN978000
序列 ASGSFKLNKK AASGEAKPKV KKAGGTKPKK PVGAAKKPKK AAGGATPKKS
预测反应 Cow: 86%, Dog: 86%, Guinea Pig: 93%, Horse: 86%, Human: 100%, Mouse: 86%, Rabbit: 85%, Rat: 86%
产品特性 This is a rabbit polyclonal antibody against HIST1H1C. It was validated on Western Blot using a cell lysate as a positive control.
纯化方法 Affinity Purified
别名 HIST1H1C (HIST1H1C Antibody 摘要)
背景 Histones are basic nuclear proteins responsible for nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures.Histones are basic nuclear proteins responsible for nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H1 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: H1.2, H1F2, MGC3992, H1C
Protein Interaction Partner: UBC, CEP250, ATRX, HIST1H3A, LEO1, PAF1, CUL4A, POLR2A, MDM2, ASB16, ASB9, SUZ12, EED, RNF2, APEH, SEC24D, TBCD, PARK2, VHL, UBD, ICAM1, CD81, IGSF8, EIF2AK2, ITGA4, IL7R, CSNK2A2, SMURF1, HIST1H2AD, H1FX, COPS5, CAND1, CUL1, CUL2, CUL3, CUL4B, CUL5, NEDD
Protein Size: 213
分子量 21 kDa
基因ID 3006
NCBI登录号 NM_005319, NP_005310
UniProt P16403
应用备注 Optimal working dilutions should be determined experimentally by the investigator.
说明

Antigen size: 213 AA

限制 仅限研究用
状态 Liquid
浓度 Lot specific
缓冲液 Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
储存液 Sodium azide
注意事项 This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
注意事项 Avoid repeated freeze-thaw cycles.
储存条件 -20 °C
储存方法 For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
厂商提供的图像
Western Blotting (WB) image for anti-Histone Cluster 1, H1c (HIST1H1C) (Middle Region) antibody (ABIN2782497) WB Suggested Anti-HIST1H1C Antibody Titration: 0.2-1 ug/ml
Positive Cont...
背景 Kim, Choi, Heo, Kim, Levens, Kohno, Johnson, Brock, An: "Isolation and characterization of a novel H1.2 complex that acts as a repressor of p53-mediated transcription." in: The Journal of biological chemistry, Vol. 283, Issue 14, pp. 9113-26, 2008 (PubMed).

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