Protein O-Fucosyltransferase 2 (POFUT2) (N-Term) 抗体

ABIN2782385 产品详细信息, 供应商: Log in to see
抗原
  • C21orf80
  • FUT13
  • fc46a11
  • wu:fc46a11
  • zgc:194822
  • 2310011G23Rik
  • AI256847
  • BC003494
  • protein O-fucosyltransferase 2
  • POFUT2
  • pofut2
  • Pofut2
抗原表位
N-Term
10
10
9
7
4
3
2
1
1
1
适用
牛, 犬, 豚鼠, 马, 人, 小鼠, 大鼠, 斑马鱼
53
11
7
1
1
1
1
1
1
1
1
宿主

44
9
克隆类型
多克隆
标记
非结合性
2
2
2
2
2
2
应用范围
Western Blotting (WB)
43
25
23
11
7
1
1
1
选项
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免疫原 The immunogen is a synthetic peptide directed towards the N terminal region of human POFUT2
Blocking Peptide Blocking peptide for this product available: ABIN981934
序列 GAASRRRYLL YDVNPPEGFN LRRDVYIRIA SLLKTLLKTE EWVLVLPPWG
预测反应 Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 100%
产品特性 This is a rabbit polyclonal antibody against POFUT2. It was validated on Western Blot using a cell lysate as a positive control.
纯化方法 Affinity Purified
别名 POFUT2 (POFUT2 Antibody 摘要)
背景 POFUT2 catalyzes the reaction that attaches fucose through an O-glycosidic linkage to a conserved serine or threonine residue in thrombospondin type 1 repeats. Fucose is typically found as a terminal modification of branched chain glycoconjugates, but it also exists in direct O-linkage to serine or threonine residues within cystine knot motifs in epidermal growth factor (EGF, MIM 131530)-like repeats or thrombospondin (THBS, see MIM 188060) type-1 repeats. POFUT2 is an O-fucosyltransferase that use THBS type-1 repeats as substrates (Luo et al., 2006 [PubMed 16464857]).[supplied by OMIM].
Alias Symbols: C21orf80, FUT13
Protein Interaction Partner: USP22,
Protein Size: 429
分子量 50 kDa
基因ID 23275
NCBI登录号 NM_133635, NP_598368
UniProt Q9Y2G5
研究领域 Signaling, Metabolism, Organelles
应用备注 Optimal working dilutions should be determined experimentally by the investigator.
说明

Antigen size: 429 AA

限制 仅限研究用
状态 Liquid
浓度 Lot specific
缓冲液 Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
储存液 Sodium azide
注意事项 This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
注意事项 Avoid repeated freeze-thaw cycles.
储存条件 -20 °C
储存方法 For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
厂商提供的图像
Western Blotting (WB) image for anti-Protein O-Fucosyltransferase 2 (POFUT2) (N-Term) antibody (ABIN2782385) anti-Protein O-Fucosyltransferase 2 (POFUT2) (N-Term) antibody
背景 Luo, Nita-Lazar, Haltiwanger: "Two distinct pathways for O-fucosylation of epidermal growth factor-like or thrombospondin type 1 repeats." in: The Journal of biological chemistry, Vol. 281, Issue 14, pp. 9385-92, 2006 (PubMed).

有引用在: Luo, Koles, Vorndam, Haltiwanger, Panin: "Protein O-fucosyltransferase 2 adds O-fucose to thrombospondin type 1 repeats." in: The Journal of biological chemistry, Vol. 281, Issue 14, pp. 9393-9, 2006 (PubMed).

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