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TIM3 抗体 (N-Term)

TIM 3 适用: 人, 犬 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2782255
发货至: 中国
  • 抗原 See all TIM3 (TIM 3) 抗体
    TIM3 (TIM 3) (Hepatitis A Virus Cellular Receptor 2 (TIM 3))
    抗原表位
    • 20
    • 7
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    • 69
    • 34
    • 4
    • 2
    • 2
    • 1
    人, 犬
    宿主
    • 48
    • 24
    • 23
    • 2
    克隆类型
    • 53
    • 43
    • 1
    多克隆
    标记
    • 58
    • 8
    • 7
    • 7
    • 7
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This TIM3 antibody is un-conjugated
    应用范围
    • 43
    • 40
    • 35
    • 23
    • 12
    • 8
    • 5
    • 5
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    序列
    MFSHLPFDCV LLLLLLLLTR SSEVEYRAEV GQNAYLPCFY TPAAPGNLVP
    预测反应
    Dog: 79%, Human: 100%
    产品特性
    This is a rabbit polyclonal antibody against HAVCR2. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the N terminal region of human HAVCR2
    Top Product
    Discover our top product TIM 3 Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 301 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    TIM3 (TIM 3) (Hepatitis A Virus Cellular Receptor 2 (TIM 3))
    别名
    HAVCR2 (TIM 3 产品)
    别名
    HAVCR2 antibody, MGC140131 antibody, HAVcr-2 antibody, KIM-3 antibody, TIM3 antibody, TIMD-3 antibody, TIMD3 antibody, Tim-3 antibody, TIM-3 antibody, Tim3 antibody, Timd3 antibody, tim3 antibody, hepatitis A virus cellular receptor 2 antibody, HAVCR2 antibody, Havcr2 antibody
    物质类
    Virus
    背景
    HAVCR2 regulates macrophage activation. HAVCR2 inhibits T-helper type 1 lymphocyte (Th1)-mediated auto- and alloimmune responses and promotes immunological tolerance. HAVCR2 may be also involved in T-cell homing. HAVCR2 is the receptor for LGALS9.CD4 (MIM 186940)-positive T helper lymphocytes can be divided into types 1 (Th1) and 2 (Th2) on the basis of their cytokine secretion patterns. Th1 cells and their associated cytokines are involved in cell-mediated immunity to intracellular pathogens and delayed-type hypersensitivity reactions, whereas Th2 cells are involved in the control of extracellular helminthic infections and the promotion of atopic and allergic diseases. The 2 types of cells also cross-regulate the functions of the other. TIM3 is a Th1-specific cell surface protein that regulates macrophage activation and enhances the severity of experimental autoimmune encephalomyelitis in mice.[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    Alias Symbols: FLJ14428, KIM-3, TIM3, TIMD3, Tim-3, TIMD-3, HAVcr-2
    Protein Interaction Partner: BAG6, LCK, APP, HAVCR2,
    Protein Size: 301
    分子量
    33 kDa
    基因ID
    84868
    NCBI登录号
    NM_032782, NP_116171
    UniProt
    Q8TDQ0
    途径
    Regulation of Lipid Metabolism by PPARalpha, Cancer Immune Checkpoints
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