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ATP2A2 抗体 (C-Term)

ATP2A2 适用: 人, 小鼠, 大鼠, 兔, 犬, Cow, 豚鼠, 马, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2782136
发货至: 中国
  • 抗原 See all ATP2A2 抗体
    ATP2A2 (ATPase, Ca++ Transporting, Cardiac Muscle, Slow Twitch 2 (ATP2A2))
    抗原表位
    • 8
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    • 3
    • 2
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    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
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    • 1
    C-Term
    适用
    • 54
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    • 28
    • 5
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    • 3
    • 3
    • 3
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    • 3
    • 2
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    • 2
    • 1
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    • 1
    人, 小鼠, 大鼠, 兔, 犬, Cow, 豚鼠, 马, 斑马鱼
    宿主
    • 53
    • 1
    • 1
    克隆类型
    • 45
    • 10
    多克隆
    标记
    • 27
    • 5
    • 4
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    • 2
    • 2
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    This ATP2A2 antibody is un-conjugated
    应用范围
    • 37
    • 23
    • 13
    • 8
    • 7
    • 5
    • 4
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    序列
    VNLVTDGLPA TALGFNPPDL DIMNKPPRNP KEPLISGWLF FRYLAIGCYV
    预测反应
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
    产品特性
    This is a rabbit polyclonal antibody against ATP2A2. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the C terminal region of human ATP2A2
    Top Product
    Discover our top product ATP2A2 Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 1042 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    ATP2A2 (ATPase, Ca++ Transporting, Cardiac Muscle, Slow Twitch 2 (ATP2A2))
    别名
    ATP2A2 (ATP2A2 产品)
    别名
    atp2b antibody, ca-p60a antibody, dar antibody, serca2 antibody, ATP2A2 antibody, ATP2B antibody, DAR antibody, DD antibody, SERCA2 antibody, SERCA2A antibody, ATP2 antibody, Serca2 antibody, SercaII antibody, 9530097L16Rik antibody, D5Wsu150e antibody, SERCA2B antibody, mKIAA4195 antibody, atp2a2 antibody, zgc:55380 antibody, ATPase, Ca++ transporting, cardiac muscle, fast twitch 1 S homeolog antibody, ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 antibody, ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 antibody, ATPase, Ca++ transporting, cardiac muscle, slow twitch 2a antibody, atp2a1.S antibody, ATP2A2 antibody, Atp2a2 antibody, atp2a2a antibody
    背景
    ATP2A2 is one of the SERCA Ca(2+)-ATPases, which are intracellular pumps located in the sarcoplasmic or endoplasmic reticula of muscle cells. This enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol into the sarcoplasmic reticulum lumen, and is involved in regulation of the contraction/relaxation cycle. Mutations in this gene cause Darier-White disease, also known as keratosis follicularis, an autosomal dominant skin disorder characterized by loss of adhesion between epidermal cells and abnormal keratinization. Alternative splicing results in multiple transcript variants encoding different isoforms.This gene encodes one of the SERCA Ca(2+)-ATPases, which are intracellular pumps located in the sarcoplasmic or endoplasmic reticula of muscle cells. This enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the sarcoplasmic reticulum lumen, and is involved in regulation of the contraction/relaxation cycle. Mutations in this gene cause Darier-White disease, also known as keratosis follicularis, an autosomal dominant skin disorder characterized by loss of adhesion between epidermal cells and abnormal keratinization. Alternative splicing results in two transcript variants encoding different isoforms.
    Alias Symbols: ATP2B, DAR, DD, DKFZp686P0211, FLJ20293, FLJ38063, MGC45367, SERCA2
    Protein Interaction Partner: ERLIN2, UBC, SUMO2, SPRTN, PTPLAD1, LGR4, MDM2, ASB14, ASB5, ASB17, ASB1, TRIM13, SUZ12, RNF2, EZH2, rev, S100A1, EGFR, ADRB2, ILK, CLN5, CLN3, env, NOS2, ATF2, CFTR, MDC1, ECT2, SLC3A2, ITPR3, CUL3, FBXO25, SPP1, SIRT7, ELAVL1, SUMO1, AMFR, HDAC5, CAMK2A
    Protein Size: 1042
    分子量
    115 kDa
    基因ID
    488
    NCBI登录号
    NM_170665, NP_733765
    UniProt
    P16615
    途径
    Myometrial Relaxation and Contraction, ER-Nucleus Signaling, Ribonucleoside Biosynthetic Process
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