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CDS1 抗体 (Middle Region)

CDS1 适用: 人, 小鼠, 大鼠, Cow, 兔, 犬, 豚鼠, 马 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2782121
发货至: 中国
  • 抗原 See all CDS1 抗体
    CDS1 (CDP-Diacylglycerol Synthase (Phosphatidate Cytidylyltransferase) 1 (CDS1))
    抗原表位
    • 5
    • 1
    • 1
    • 1
    • 1
    Middle Region
    适用
    • 11
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠, Cow, 兔, 犬, 豚鼠, 马
    宿主
    • 10
    • 1
    克隆类型
    • 10
    • 1
    多克隆
    标记
    • 7
    • 2
    • 1
    • 1
    This CDS1 antibody is un-conjugated
    应用范围
    • 6
    • 5
    • 2
    • 1
    • 1
    Western Blotting (WB)
    序列
    VVFGFIAAYV LSKYQYFVCP VEYRSDVNSF VTECEPSELF QLQTYSLPPF
    预测反应
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
    产品特性
    This is a rabbit polyclonal antibody against CDS1. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the middle region of human CDS1
    Top Product
    Discover our top product CDS1 Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 461 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Croston, Shepherd, Thapa, Nichols, Lewis, Dabkowski, Jagannathan, Baseler, Hollander: "Evaluation of the cardiolipin biosynthetic pathway and its interactions in the diabetic heart." in: Life sciences, Vol. 93, Issue 8, pp. 313-22, (2013) (PubMed).

  • 抗原
    CDS1 (CDP-Diacylglycerol Synthase (Phosphatidate Cytidylyltransferase) 1 (CDS1))
    别名
    CDS1 (CDS1 产品)
    别名
    CDS antibody, 4833409J18Rik antibody, AI314024 antibody, AW125888 antibody, CDP-diacylglycerol synthase 1 antibody, CDS1 antibody, Cds1 antibody
    背景
    Breakdown products of phosphoinositides are ubiquitous second messengers that function downstream of many G protein-coupled receptors and tyrosine kinases regulating cell growth, calcium metabolism, and protein kinase C activity. CDS1 is an enzyme which regulates the amount of phosphatidylinositol available for signaling by catalyzing the conversion of phosphatidic acid to CDP-diacylglycerol. This enzyme is an integral membrane protein localized to two subcellular domains, the matrix side of the inner mitochondrial membrane where it is thought to be involved in the synthesis of phosphatidylglycerol and cardiolipin and the cytoplasmic side of the endoplasmic reticulum where it functions in phosphatidylinositol biosynthesis.Breakdown products of phosphoinositides are ubiquitous second messengers that function downstream of many G protein-coupled receptors and tyrosine kinases regulating cell growth, calcium metabolism, and protein kinase C activity. This gene encodes an enzyme which regulates the amount of phosphatidylinositol available for signaling by catalyzing the conversion of phosphatidic acid to CDP-diacylglycerol. This enzyme is an integral membrane protein localized to two subcellular domains, the matrix side of the inner mitochondrial membrane where it is thought to be involved in the synthesis of phosphatidylglycerol and cardiolipin and the cytoplasmic side of the endoplasmic reticulum where it functions in phosphatidylinositol biosynthesis. Two genes encoding this enzyme have been identified in humans, one mapping to human chromosome 4q21 and a second to 20p13.
    Alias Symbols: CDS
    Protein Interaction Partner: UBC, CDC25C,
    Protein Size: 461
    分子量
    53 kDa
    基因ID
    1040
    NCBI登录号
    NM_001263, NP_001254
    UniProt
    Q92903
    途径
    Inositol Metabolic Process
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