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ABCA7 抗体 (Middle Region)

ABCA7 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2781526
发货至: 中国
  • 抗原 See all ABCA7 抗体
    ABCA7 (ATP-Binding Cassette, Sub-Family A (ABC1), Member 7 (ABCA7))
    抗原表位
    • 16
    • 2
    • 1
    • 1
    • 1
    • 1
    Middle Region
    适用
    人, 小鼠, 大鼠, Cow, 犬, 豚鼠
    宿主
    • 26
    • 2
    克隆类型
    • 26
    • 2
    多克隆
    标记
    • 9
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ABCA7 antibody is un-conjugated
    应用范围
    • 20
    • 13
    • 13
    • 7
    • 6
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB)
    序列
    DTQTRHLSGG MQRKLSVAIA FVGGSRVVIM DEPTAGVDPA SRRGIWELLL
    预测反应
    Cow: 93%, Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 93%, Rat: 100%
    产品特性
    This is a rabbit polyclonal antibody against Abca7. It was validated on Western Blot.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide corresponding to a region of Mouse
    Top Product
    Discover our top product ABCA7 Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 2159 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Bamji-Mirza, Li, Najem, Liu, Walker, Lue, Stupak, Chan, Li, Ghani, Yang, Rogaeva, Zhang: "Genetic Variations in ABCA7 Can Increase Secreted Levels of Amyloid-β40 and Amyloid-β42 Peptides and ABCA7 Transcription in Cell Culture Models." in: Journal of Alzheimer's disease : JAD, Vol. 53, Issue 3, pp. 875-92, (2016) (PubMed).

  • 抗原
    ABCA7 (ATP-Binding Cassette, Sub-Family A (ABC1), Member 7 (ABCA7))
    别名
    Abca7 (ABCA7 产品)
    别名
    ABCX antibody, Abc51 antibody, ABCA-SSN antibody, ABCA7 antibody, ATP-binding cassette, sub-family A (ABC1), member 7 antibody, ATP binding cassette subfamily A member 7 antibody, ATP-binding cassette sub-family A member 7 antibody, Abca7 antibody, ABCA7 antibody, LOC100088822 antibody
    背景
    Abca7 plays a role in phagocytosis by macrophages of apoptotic cells.Abca7 binds APOA1 and may function in apolipoprotein-mediated phospholipid efflux from cells. Abca7 may also mediate cholesterol efflux. Abca7 may regulate cellular ceramide homeostasis during keratinocytes differentiation.
    Alias Symbols: ABCX, Abc51
    Protein Size: 2159
    分子量
    237 kDa
    基因ID
    27403
    NCBI登录号
    NM_013850, NP_038878
    UniProt
    Q91V24
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