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NR4A2 抗体 (N-Term)

NR4A2 适用: 人, 小鼠, 大鼠, 斑马鱼, 犬, 豚鼠, 马, 兔, Cow WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2780752
发货至: 中国
  • 抗原 See all NR4A2 抗体
    NR4A2 (Nuclear Receptor Subfamily 4, Group A, Member 2 (NR4A2))
    抗原表位
    • 15
    • 15
    • 6
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    • 60
    • 45
    • 40
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    人, 小鼠, 大鼠, 斑马鱼, 犬, 豚鼠, 马, 兔, Cow
    宿主
    • 61
    • 3
    克隆类型
    • 61
    • 3
    多克隆
    标记
    • 34
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This NR4A2 antibody is un-conjugated
    应用范围
    • 61
    • 26
    • 26
    • 17
    • 13
    • 12
    • 9
    • 7
    • 5
    • 4
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    序列
    MPCVQAQYGS SPQGASPASQ SYSYHSSGEY SSDFLTPEFV KFSMDLTNTE
    预测反应
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
    产品特性
    This is a rabbit polyclonal antibody against NR4A2. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the N terminal region of human NR4A2
    Top Product
    Discover our top product NR4A2 Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 598 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Brami-Cherrier, Anzalone, Ramos, Forne, Macciardi, Imhof, Borrelli: "Epigenetic reprogramming of cortical neurons through alteration of dopaminergic circuits." in: Molecular psychiatry, Vol. 19, Issue 11, pp. 1193-200, (2014) (PubMed).

  • 抗原
    NR4A2 (Nuclear Receptor Subfamily 4, Group A, Member 2 (NR4A2))
    别名
    NR4A2 (NR4A2 产品)
    别名
    nr41/42/43 antibody, Nr4a2 antibody, nurr1 antibody, not antibody, rnr1 antibody, hzf-3 antibody, tinur antibody, NGFI-B antibody, HZF-3 antibody, NOT antibody, NURR1 antibody, RNR1 antibody, TINUR antibody, Nurr1 antibody, RNR-1 antibody, TINOR antibody, ngf1b antibody, nr4a2 antibody, zgc:92696 antibody, nuclear receptor subfamily 4 group A member 2 antibody, nuclear receptor antibody, nuclear receptor subfamily 4, group A, member 2 antibody, nuclear receptor subfamily 4, group A, member 2b antibody, NR4A2 antibody, nr41/42/43 antibody, nr4a2 antibody, Nr4a2 antibody, nr4a2b antibody
    背景
    NR4A2 is a member of the steroid-thyroid hormone-retinoid receptor superfamily. The protein may act as a transcription factor. Mutations in NR4A2 gene have been associated with disorders related to dopaminergic dysfunction, including Parkinson disease, schizophernia, and manic depression. Misregulation of NR4A2 gene may be associated with rheumatoid arthritis.This gene encodes a member of the steroid-thyroid hormone-retinoid receptor superfamily. The encoded protein may act as a transcription factor. Mutations in this gene have been associated with disorders related to dopaminergic dysfunction, including Parkinson disease, schizophernia, and manic depression. Misregulation of this gene may be associated with rheumatoid arthritis. Four transcript variants encoding four distinct isoforms have been identified for this gene. Additional alternate splice variants may exist, but their full length nature has not been determined.This gene encodes a member of the steroid-thyroid hormone-retinoid receptor superfamily. The encoded protein may act as a transcription factor. Mutations in this gene have been associated with disorders related to dopaminergic dysfunction, including Parkinson disease, schizophernia, and manic depression. Misregulation of this gene may be associated with rheumatoid arthritis. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    Alias Symbols: HZF-3, NOT, NURR1, RNR1, TINUR
    Protein Interaction Partner: CDKN2D, TCEAL5, BAZ1B, ELAVL1, COPS5, RXRB, RXRA, RUNX1, SMARCA4, SMARCA2, SIN3A, NCOR2, SFPQ, PIAS4, RPS6KA1, CDKN1C, RARB, RARA, CREB1,
    Protein Size: 598
    分子量
    66 kDa
    基因ID
    4929
    NCBI登录号
    NM_006186, NP_006177
    UniProt
    P43354
    途径
    Nuclear Receptor Transcription Pathway, Dopaminergic Neurogenesis, Steroid Hormone Mediated Signaling Pathway
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