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NR1D2 抗体 (N-Term)

NR1D2 适用: 人, 大鼠, 小鼠, 犬, 兔, Cow, 马, 豚鼠 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2780649
发货至: 中国
  • 抗原 See all NR1D2 抗体
    NR1D2 (Nuclear Receptor Subfamily 1, Group D, Member 2 (NR1D2))
    抗原表位
    • 15
    • 8
    • 7
    • 7
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    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    • 52
    • 8
    • 6
    • 6
    • 6
    • 6
    • 5
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
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    人, 大鼠, 小鼠, 犬, 兔, Cow, 马, 豚鼠
    宿主
    • 49
    • 5
    克隆类型
    • 50
    • 4
    多克隆
    标记
    • 26
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    This NR1D2 antibody is un-conjugated
    应用范围
    • 30
    • 23
    • 18
    • 13
    • 13
    • 7
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    序列
    YISSSSSASS HASCHSEGSE NSFQSSSSSV PSSPNSSNSD TNGNPKNGDL
    预测反应
    Cow: 79%, Dog: 93%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 86%, Rabbit: 100%, Rat: 93%
    产品特性
    This is a rabbit polyclonal antibody against NR1D2. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the N terminal region of human NR1D2
    Top Product
    Discover our top product NR1D2 Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 579 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    NR1D2 (Nuclear Receptor Subfamily 1, Group D, Member 2 (NR1D2))
    别名
    NR1D2 (NR1D2 产品)
    别名
    BD73 antibody, EAR-1R antibody, RVR antibody, HZF-2 antibody, Rev-erb antibody, REV-ERBB antibody, NR1D2 antibody, rvr antibody, bd73 antibody, hzf2 antibody, ear-1r antibody, hs.37288 antibody, NR1D2-A antibody, Reverbbeta-A antibody, reverbb1 antibody, reverbb antibody, reverbb2 antibody, zgc:92019 antibody, nuclear receptor subfamily 1 group D member 2 antibody, nuclear receptor subfamily 1, group D, member 2 antibody, nuclear receptor subfamily 1, group D, member 2a antibody, nuclear receptor subfamily 1, group D, member 2b antibody, NR1D2 antibody, Nr1d2 antibody, nr1d2 antibody, nr1d2a antibody, nr1d2b antibody
    背景
    NR1D2 can interact with NCOA5 coactivator, leading to a strong increase of transcription of target genes. NR1D2 also binds to the sequences 5'-AATGTAGGTCA-3' and 5'-ATAACTAGGTCA-3' and acts as a potent competitive transcriptional silencer and negative regulator of RORalpha mediated trans-activation. NR1D2 may play different roles in metabolism, inflammation, and circadian cycling in the organ-specific manner in homeostasis.
    Alias Symbols: BD73, EAR-1r, HZF2, Hs.37288, RVR, EAR-1R
    Protein Interaction Partner: MID2, RBPMS, TRIM27, NOTCH2NL, KRTAP10-9, KRT40, KRTAP4-2, PRMT6, SKP1, UBC, SIN3B, KAT5, NCOR1, TAF9, TAF6, HDAC1, GTF2B, NCOA5, UBE2I, CUL1, NR1D1, RGN,
    Protein Size: 579
    分子量
    65 kDa
    基因ID
    9975
    NCBI登录号
    NM_005126, NP_005117
    UniProt
    Q14995
    途径
    Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway
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