SPI1 抗体 (Middle Region)
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- 抗原 See all SPI1 抗体
- SPI1 (Spleen Focus Forming Virus (SFFV) Proviral Integration Oncogene Spi1 (SPI1))
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抗原表位
- Middle Region
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适用
- 人, 小鼠, 大鼠, Pig, 犬, Cow, 马, 豚鼠, 斑马鱼
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This SPI1 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- QKGNRKKMTY QKMARALRNY GKTGEVKKVK KKLTYQFSGE VLGRGGLAER
- 预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 85%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rat: 100%, Zebrafish: 100%
- 产品特性
- This is a rabbit polyclonal antibody against SPI1. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human SPI1
- Top Product
- Discover our top product SPI1 Primary Antibody
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anti-Spleen Focus Forming Virus (SFFV) Proviral Integration Oncogene Spi1 (SPI1) (AA 16-170) antibody
SPI1 适用: 人 WB, IHC, IF, FACS, StM 宿主: 小鼠 Monoclonal PU1-2146 unconjugated
anti-Spleen Focus Forming Virus (SFFV) Proviral Integration Oncogene Spi1 (SPI1) (AA 124-271) antibodySPI1 适用: 人 WB, ELISA, FACS 宿主: 小鼠 Monoclonal 5C7 unconjugated
anti-Spleen Focus Forming Virus (SFFV) Proviral Integration Oncogene Spi1 (SPI1) (AA 1-120) antibodySPI1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 2G1 unconjugated
anti-Spleen Focus Forming Virus (SFFV) Proviral Integration Oncogene Spi1 (SPI1) (Internal Region) antibodyVerified SPI1 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Spleen Focus Forming Virus (SFFV) Proviral Integration Oncogene Spi1 (SPI1) (AA 1-122) antibodySPI1 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Spleen Focus Forming Virus (SFFV) Proviral Integration Oncogene Spi1 (SPI1) (AA 217-246) antibodySPI1 适用: 人 WB, IHC, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Spleen Focus Forming Virus (SFFV) Proviral Integration Oncogene Spi1 (SPI1) (AA 1-264) antibodySPI1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Spleen Focus Forming Virus (SFFV) Proviral Integration Oncogene Spi1 (SPI1) (AA 20-70) antibodySPI1 适用: 人, 小鼠, 犬, Cow, 马, 猴 WB, FACS 宿主: 兔 Polyclonal unconjugated
anti-Spleen Focus Forming Virus (SFFV) Proviral Integration Oncogene Spi1 (SPI1) (AA 18-196) antibodySPI1 适用: 人, 小鼠, 大鼠 IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Spleen Focus Forming Virus (SFFV) Proviral Integration Oncogene Spi1 (SPI1) (AA 217-246), (C-Term) antibodySPI1 适用: 人 WB, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 270 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- SPI1 (Spleen Focus Forming Virus (SFFV) Proviral Integration Oncogene Spi1 (SPI1))
- 别名
- SPI1 (SPI1 产品)
- 背景
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SPI1 is known to collaborate with multiple transcription factors and to regulate expression of immunoglobulin genes. Lack of SPI1 expression is associated with defective immunoglobulin transcription in Hodgkin and Reed-Sternberg cells of classical Hodgkin disease. This gene encodes an ETS-domain transcription factor that activates gene expression during myeloid and B-lymphoid cell development. The nuclear protein binds to a purine-rich sequence known as the PU-box found near the promoters of target genes, and regulates their expression in coordination with other transcription factors and cofactors. The protein can also regulate alternative splicing of target genes. Multiple transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: OF, PU.1, SFPI1, SPI-1, SPI-A
Protein Interaction Partner: HOXA10, TMX1, VAV1, IRF1, IRF8, GATA3, GATA2, GATA1, GFI1, TBP, RB1, BYRF1, RARA, PML, HDAC3, SKI, SIN3A, HDAC1, BCL6, CEBPA, PIP, SPIB, SSRP1, IRF4, KAT6A, CEBPE, NFATC1, CREBBP, NONO, CEBPB, JUN, ERG, NFKB1, MITF, FUS, CREM, ATF1, CEBPD, MECP2, DNMT3B,
Protein Size: 270 - 分子量
- 31 kDa
- 基因ID
- 6688
- NCBI登录号
- NM_003120, NP_003111
- UniProt
- P17947
- 途径
- Stem Cell Maintenance
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