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SOX9 抗体 (SRY (Sex Determining Region Y)-Box 9) (C-Term)

Details for Product anti-SOX9 Antibody No. ABIN2780338, 供应商: Log in to see
抗原
  • LOC100227849
  • SOX9
  • CMD1
  • CMPD1
  • SRA1
  • SOX-9
  • 2010306G03Rik
  • AV220920
  • mKIAA4243
  • SRY (sex determining region Y)-box 9
  • SRY (sex determining region Y)-box 10
  • SRY-box containing gene 9
  • SOX9
  • LOC100227849
  • SOX10
  • Sox9
Alternatives
anti-人 SOX9 抗体 for Immunofluorescence (fixed cells)
抗原表位
C-Term
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9
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适用
牛, 犬, 豚鼠, 马, 人, 小鼠, 猪, 兔, 大鼠, 斑马鱼
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59
38
15
9
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宿主

136
65
6
克隆类型
多克隆
标记
This SOX9 antibody is un-conjugated
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应用范围
Flow Cytometry (FACS), Western Blotting (WB)
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95
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53
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14
7
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Supplier
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免疫原 The immunogen is a synthetic peptide directed towards the C terminal region of human SOX9
Blocking Peptide Blocking peptide for this product available: ABIN984286
序列 AGQGTGLYST FTYMNPAQRP MYTPIADTSG VPSIPQTHSP QHWEQPVYTQ
预测反应 Cow: 86%, Dog: 100%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%
产品特性 This is a rabbit polyclonal antibody against SOX9. It was validated on Western Blot using a cell lysate as a positive control.
纯化方法 Affinity Purified
别名 SOX9 (SOX9 Antibody 摘要)
背景 SOX9 recognizes the sequence CCTTGAG along with other members of the HMG-box class DNA-binding proteins. It acts during chondrocyte differentiation and, with steroidogenic factor 1, regulates transcription of the anti-Muellerian hormone (AMH) gene. Deficiencies lead to the skeletal malformation syndrome campomelic dysplasia, frequently with sex reversal.The protein encoded by this gene recognizes the sequence CCTTGAG along with other members of the HMG-box class DNA-binding proteins. It acts during chondrocyte differentiation and, with steroidogenic factor 1, regulates transcription of the anti-Muellerian hormone (AMH) gene. Deficiencies lead to the skeletal malformation syndrome campomelic dysplasia, frequently with sex reversal. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: CMD1, CMPD1, SRA1
Protein Interaction Partner: ZBTB7A, SCX, HERC1, UBC, SOX9, ATP6V1H, ctnnb1-a, RUNX2, SMAD3, SMAD2, EP300, CREB3L4, SPEN, KPNB1, TRAF2, CREBBP, MED12, NR5A1, MAF, HSPA1A, CREB1,
Protein Size: 509
分子量 56 kDa
基因ID 6662
NCBI登录号 NM_000346, NP_000337
UniProt P48436
研究领域 Organogenesis, Reproduction, Lineage Markers, Transcription Factors
途径 EGFR Signaling Pathway, Stem Cell Maintenance, Regulation of Muscle Cell Differentiation, Tube Formation, Skeletal Muscle Fiber Development
应用备注 Optimal working dilutions should be determined experimentally by the investigator.
说明

Antigen size: 509 AA

限制 仅限研究用
状态 Liquid
浓度 Lot specific
缓冲液 Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
储存液 Sodium azide
注意事项 This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
注意事项 Avoid repeated freeze-thaw cycles.
储存条件 -20 °C
储存方法 For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
厂商提供的图像
Western Blotting (WB) image for anti-SOX9 抗体 (SRY (Sex Determining Region Y)-Box 9) (C-Term) (ABIN2780338) WB Suggested Anti-SOX9 Antibody Titration: 0.2-1 ug/ml
Positive Control:...
有引用在: Lau, Lee, Chang: "Conserved sex-specific timing of meiotic initiation during sex differentiation in the protandrous black porgy Acanthopagrus schlegelii." in: Biology of reproduction, Vol. 88, Issue 6, pp. 150, 2013 (PubMed).

背景 Vidal, Ortonne, Schedl: "SOX9 expression is a general marker of basal cell carcinoma and adnexal-related neoplasms." in: Journal of cutaneous pathology, Vol. 35, Issue 4, pp. 373-9, 2008 (PubMed).