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CHEK1 抗体 (Middle Region)

CHEK1 适用: 人, 小鼠, 大鼠, 犬, 兔, Cow, 马, 豚鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2779737
发货至: 中国
  • 抗原 See all CHEK1 抗体
    CHEK1 (Checkpoint Kinase 1 (CHEK1))
    抗原表位
    • 44
    • 29
    • 26
    • 19
    • 14
    • 13
    • 7
    • 6
    • 5
    • 4
    • 3
    • 2
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    Middle Region
    适用
    • 214
    • 118
    • 67
    • 16
    • 9
    • 8
    • 6
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
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    • 1
    人, 小鼠, 大鼠, 犬, 兔, Cow, 马, 豚鼠
    宿主
    • 223
    • 14
    • 7
    • 5
    克隆类型
    • 209
    • 41
    多克隆
    标记
    • 134
    • 13
    • 11
    • 9
    • 9
    • 9
    • 9
    • 8
    • 8
    • 8
    • 5
    • 5
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    • 4
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    This CHEK1 antibody is un-conjugated
    应用范围
    • 172
    • 87
    • 53
    • 41
    • 40
    • 36
    • 35
    • 17
    • 16
    • 13
    • 10
    • 7
    • 6
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    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    序列
    SARITIPDIK KDRWYNKPLK KGAKRPRVTS GGVSESPSGF SKHIQSNLDF
    预测反应
    Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
    产品特性
    This is a rabbit polyclonal antibody against CHEK1. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the middle region of human CHEK1
    Top Product
    Discover our top product CHEK1 Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 476 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    CHEK1 (Checkpoint Kinase 1 (CHEK1))
    别名
    CHEK1 (CHEK1 产品)
    别名
    An08g10320 antibody, AO090003000441 antibody, CHK1 antibody, chk1 antibody, C85740 antibody, Chk1 antibody, rad27 antibody, id:ibd2720 antibody, zgc:56093 antibody, CHEK1 antibody, checkpoint kinase 1 antibody, serine/threonine-protein kinase chk1 antibody, serine/threonine-protein kinase Chk1 antibody, CAMK/CAMKL/CHK1 protein kinase Chk1 antibody, checkpoint kinase 1 S homeolog antibody, CHEK1 antibody, ANI_1_2436074 antibody, AOR_1_768154 antibody, PTRG_04183 antibody, SJAG_01680 antibody, PAAG_04978 antibody, MCYG_03290 antibody, VDBG_03742 antibody, chek1.S antibody, Chek1 antibody, chek1 antibody
    背景
    CHEK1 is required during normal S phase to avoid aberrantly increased initiation of DNA replication, thereby protecting against DNA breakage. Its expression is dispensable for somatic cell death and critical for sustaining G2 DNA damage checkpoint.
    Alias Symbols: CHK1
    Protein Interaction Partner: RELA, CUL4A, UBC, SETMAR, DDB1, TNRC6B, ATR, HECW2, CLSPN, DTL, BTG3, TOPBP1, MAPKAPK2, HSP90AA1, CDC25C, RAD51, PIGM, CUL1, VCP, CDC25A, ATM, APP, MED15, NEK2, TLK1, RB1, BRCA1, FEM1B, XIAP, COPS5, MEPE, LATS2, TP53, Chek1, MEN1, USP7, DNMT1, FANCE, PCNA
    Protein Size: 476
    分子量
    54 kDa
    基因ID
    1111
    NCBI登录号
    NM_001274, NP_001265
    UniProt
    O14757
    途径
    p53 Pathway, Apoptosis, Cell Division Cycle, DNA Damage Repair
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