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Src 抗体 (N-Term)

Src 适用: 人, 小鼠, 大鼠, Cow, 犬, 兔, 豚鼠 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2779668
发货至: 中国
  • 抗原 See all Src 抗体
    Src (Proto-oncogene tyrosine-protein kinase Src (Src))
    抗原表位
    • 27
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    • 1
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    N-Term
    适用
    • 224
    • 143
    • 120
    • 9
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    • 5
    • 5
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    • 4
    • 3
    • 2
    • 1
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    • 1
    人, 小鼠, 大鼠, Cow, 犬, 兔, 豚鼠
    宿主
    • 237
    • 19
    • 1
    克隆类型
    • 217
    • 40
    多克隆
    标记
    • 122
    • 21
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    • 12
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    • 6
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    • 6
    • 6
    • 6
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    • 1
    This Src antibody is un-conjugated
    应用范围
    • 191
    • 134
    • 63
    • 55
    • 53
    • 35
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    • 29
    • 22
    • 12
    • 9
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    Western Blotting (WB)
    序列
    MGSNKSKPKD ASQRRRSLEP AENVHGAGGG AFPASQTPSK PASADGHRGP
    预测反应
    Cow: 85%, Dog: 92%, Guinea Pig: 92%, Human: 100%, Mouse: 100%, Rabbit: 77%, Rat: 100%
    产品特性
    This is a rabbit polyclonal antibody against SRC. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the N terminal region of human SRC
    Top Product
    Discover our top product Src Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 536 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    Src (Proto-oncogene tyrosine-protein kinase Src (Src))
    别名
    SRC (Src 产品)
    别名
    AW259666 antibody, pp60c-src antibody, C-src1 antibody, CG7524 antibody, D-Src64B antibody, D-src antibody, DSRC64 antibody, DSrc antibody, DSrc64 antibody, DSrc64B antibody, Dm SRC1 antibody, DmHD-358 antibody, Dmel\CG7524 antibody, Dsrc antibody, Dsrc64 antibody, Dsrc64B antibody, HD-358 antibody, MRE5 antibody, SRC 64B antibody, Src antibody, Src1 antibody, Src64 antibody, c-src antibody, dSrc antibody, dsrc antibody, src antibody, src1 antibody, src64 antibody, src64B antibody, src64b antibody, ASV antibody, SRC1 antibody, c-SRC antibody, p60-Src antibody, c-Src antibody, PP60C-SCR antibody, SDR antibody, SRC proto-oncogene, non-receptor tyrosine kinase antibody, uncharacterized LOC5574802 antibody, proto-oncogene tyrosine-protein kinase src antibody, Rous sarcoma oncogene antibody, Src oncogene at 64B antibody, SRC antibody, LOC5574802 antibody, CpipJ_CPIJ010659 antibody, Src antibody, Src64B antibody
    物质类
    Viral Protein
    背景
    This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. SRC protein is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. Two transcript variants encoding the same protein have been found for this gene.
    Alias Symbols: ASV, SRC1, c-SRC, p60-Src
    Protein Interaction Partner: PSMB9, POLR2L, POLR2K, POLR2J, POLR2I, POLR2H, POLR2G, POLR2F, POLR2E, POLR2D, POLR2C, POLR2B, POLR2A, NEDD4, MAPT, ESR1, CA3, ARRB2, UBC, SRC, SPRR2A, IKBKG, CBLC, ZNF658B, TLR4, RGS16, PTGER4, EGFR, ARRB1, TNFRSF1A, KHDRBS1, SYK, CD44, ENO1, ANXA7, PIK3
    Protein Size: 536
    分子量
    60 kDa
    基因ID
    6714
    NCBI登录号
    NM_198291, NP_938033
    UniProt
    P12931
    途径
    JAK/STAT Signaling, Neurotrophin Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Cellular Response to Molecule of Bacterial Origin, Cell-Cell Junction Organization, Regulation of Carbohydrate Metabolic Process, Autophagy, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, Smooth Muscle Cell Migration, Negative Regulation of intrinsic apoptotic Signaling, Platelet-derived growth Factor Receptor Signaling, Thromboxane A2 Receptor Signaling, Signaling of Hepatocyte Growth Factor Receptor, VEGF Signaling
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