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MED6 抗体 (Middle Region)

MED6 适用: 人, 小鼠, 大鼠, 犬, Cow, 马, 兔, 豚鼠, Pig WB, ChIP 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2778336
发货至: 中国
  • 抗原 See all MED6 抗体
    MED6 (Mediator Complex Subunit 6 (MED6))
    抗原表位
    • 12
    • 8
    • 7
    • 7
    • 7
    • 6
    • 6
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    适用
    • 54
    • 9
    • 6
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠, 犬, Cow, 马, 兔, 豚鼠, Pig
    宿主
    • 49
    • 5
    克隆类型
    • 51
    • 3
    多克隆
    标记
    • 27
    • 5
    • 4
    • 4
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This MED6 antibody is un-conjugated
    应用范围
    • 47
    • 31
    • 2
    • 2
    • 1
    Western Blotting (WB), Chromatin Immunoprecipitation (ChIP)
    序列
    LLLDLRQKFP PKFVQLKPGE KPVPVDQTKK EAEPIPETVK PEEKETTKNV
    预测反应
    Cow: 93%, Dog: 93%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 86%, Pig: 93%, Rabbit: 93%, Rat: 93%
    产品特性
    This is a rabbit polyclonal antibody against MED6. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the middle region of human MED6
    Top Product
    Discover our top product MED6 Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 246 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    MED6 (Mediator Complex Subunit 6 (MED6))
    别名
    MED6 (MED6 产品)
    别名
    NY-REN-28 antibody, wu:fa14c11 antibody, zgc:86933 antibody, 1500012F11Rik antibody, AU019660 antibody, AV213303 antibody, RNA polymerase transcriptional regulation mediator-like protein antibody, mediator complex subunit 6 antibody, hypothetical protein antibody, MED6 antibody, Med6 antibody, med6 antibody, CAALFM_C306170CA antibody
    背景
    MED6 is a component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. And mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
    Alias Symbols: NY-REN-28
    Protein Interaction Partner: TARDBP, UBC, CDK19, CDK8, MED10, MED23, CCNC, MED19, MED26, FBXW7, MED11, MED28, MED29, MED4, MED12, MED7, MED21, MED1, SMARCA4, BCL6, SUZ12, CUL1, SKP1, CTDP1, MED25, SREBF1, MED15, VDR, OBFC1, MED18, ZC3H13, TADA2A, RARA, PARP1, SMAD3, SMAD2, SMAD1, MED
    Protein Size: 246
    分子量
    28 kDa
    基因ID
    10001
    NCBI登录号
    NM_005466, NP_005457
    UniProt
    O75586
    途径
    Stem Cell Maintenance, Regulation of Lipid Metabolism by PPARalpha
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