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PARP1 抗体 (C-Term)

PARP1 适用: 人, 小鼠, 大鼠, 犬, Cow, 马, 兔, 豚鼠, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2778108
发货至: 中国
  • 抗原 See all PARP1 抗体
    PARP1 (Poly (ADP-Ribose) Polymerase 1 (PARP1))
    抗原表位
    • 20
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    C-Term
    适用
    • 231
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    人, 小鼠, 大鼠, 犬, Cow, 马, 兔, 豚鼠, 斑马鱼
    宿主
    • 220
    • 27
    • 1
    • 1
    克隆类型
    • 207
    • 42
    多克隆
    标记
    • 143
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    This PARP1 antibody is un-conjugated
    应用范围
    • 160
    • 130
    • 69
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    Western Blotting (WB)
    序列
    ISRLPKGKHS VKGLGKTTPD PSANISLDGV DVPLGTGISS GVIDTSLLYN
    预测反应
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
    产品特性
    This is a rabbit polyclonal antibody against PARP1. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Protein A purified
    免疫原
    The immunogen is a synthetic peptide directed towards the C terminal region of human PARP1
    Top Product
    Discover our top product PARP1 Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 1014 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    PARP1 (Poly (ADP-Ribose) Polymerase 1 (PARP1))
    别名
    PARP1 (PARP1 产品)
    别名
    ADPRT antibody, ADPRT 1 antibody, ADPRT1 antibody, ARTD1 antibody, PARP antibody, PARP-1 antibody, PPOL antibody, pADPRT-1 antibody, Adprt antibody, Parp-1 antibody, 5830444G22Rik antibody, AI893648 antibody, Adprp antibody, Adprt1 antibody, C80510 antibody, parp-1 antibody, sPARP-1 antibody, BEST:LD21673 antibody, CG17685 antibody, CG17696 antibody, CG17718 antibody, CG40411 antibody, D.PARP antibody, Dm.pARTa antibody, Dmel\\CG40411 antibody, LD21673.3prime antibody, PARP1 antibody, dPARP antibody, parp antibody, adprt1 antibody, padprt-1 antibody, ppol antibody, si:dkey-206f10.3 antibody, wu:fc60f12 antibody, zgc:110092 antibody, poly(ADP-ribose) polymerase 1 antibody, poly (ADP-ribose) polymerase 1 antibody, poly (ADP-ribose) polymerase family, member 1 antibody, Poly-(ADP-ribose) polymerase antibody, poly(ADP-ribose) polymerase 1 L homeolog antibody, PARP1 antibody, Parp1 antibody, Parp antibody, parp1.L antibody, parp1 antibody
    背景
    PARP1 encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes. PARP1 can be cleaved resulting in fragements of 29 and 85 kDa.
    Alias Symbols: C12orf6, PARP1
    Protein Interaction Partner: MDFI, TRIP13, DCAF11, RNF114, OTUD4, LYZ, GTPBP3, NUP98,
    Protein Size: 1014
    分子量
    113 kDa
    基因ID
    57097
    NCBI登录号
    NM_001618, NP_001609
    UniProt
    P09874
    途径
    Apoptosis, Caspase Cascade in Apoptosis, DNA Damage Repair, Production of Molecular Mediator of Immune Response, Maintenance of Protein Location
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