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STAT1 抗体 (N-Term)

Name: STAT1 抗体 (N-Term)
SKU: ABIN2777895
Availability: OutOfStock

STAT1 适用: 人, 小鼠, 大鼠, 犬, Cow, 绵羊, Pig, 马, 兔, 豚鼠 WB 宿主: 兔 Polyclonal unconjugated

WB Suggested Anti-STAT1 Antibody Titration: 0.

Rabbit Anti-STAT1 Antibody Catalog Number: ARP33373_P050 Formalin Fixed Paraffin Embedded Tissue: Human Lymph Node Tissue Observed Staining: Cytoplasm Primary Antibody Concentration: 1:100 Other Working Concentrations: N/A Secondary Antibody: Donkey anti-Rabbit-Cy3 Secondary Antibody Concentration: 1:200 Magnification: 20X Exposure Time: 0.

IHC

2 images

(1 reference)

产品编号 ABIN2777895

发货至: 中国

Datasheet as PDF

抗原 See all STAT1 抗体

STAT1 (Signal Transducer and Activator of Transcription 1, 91kDa (STAT1))
抗原表位
50

38

16

15

13

7

6

6

4

3

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
N-Term
适用
188

102

74

18

17

15

14

12

10

6

6

5

4

4

2

1

1
人, 小鼠, 大鼠, 犬, Cow, 绵羊, Pig, 马, 兔, 豚鼠
宿主
185

21

2
兔
Compatible Secondaries
克隆类型
164

44
多克隆
标记
115

11

11

8

6

6

5

5

5

5

5

5

3

3

3

3

3

2

2

2
This STAT1 antibody is un-conjugated
应用范围
139

67

51

46

39

32

26

26

21

8

6

4

3

2

2

1
Western Blotting (WB)

序列

MCIEHEIKSL EDLQDEYDFK CKTLQNREHE TNGVAKSDQK QEQLLLKKMY

预测反应

Cow: 92%, Dog: 84%, Guinea Pig: 92%, Horse: 84%, Human: 100%, Mouse: 90%, Pig: 84%, Rabbit: 92%, Rat: 84%, Sheep: 92%

产品特性

This is a rabbit polyclonal antibody against STAT1. It was validated on Western Blot using a cell lysate as a positive control.

纯化方法

Affinity Purified

免疫原

The immunogen is a synthetic peptide directed towards the N terminal region of human STAT1

Top Product

Discover our top product STAT1 Primary Antibody
anti-Signal Transducer and Activator of Transcription 1, 91kDa (STAT1) (pSer727) antibody
STAT1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Signal Transducer and Activator of Transcription 1, 91kDa (STAT1) (AA 343-602) antibody
STAT1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Signal Transducer and Activator of Transcription 1, 91kDa (STAT1) (pSer727) antibody
STAT1 适用: 人, 小鼠, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated

anti-Signal Transducer and Activator of Transcription 1, 91kDa (STAT1) antibody
STAT1 适用: 人, 犬, 猴 WB, IHC, IHC (p), IF 宿主: 小鼠 Monoclonal 4H9 unconjugated

anti-Signal Transducer and Activator of Transcription 1, 91kDa (STAT1) (AA 717-745), (C-Term) antibody
STAT1 适用: 人 WB, IHC (p), IF, FACS 宿主: 兔 Polyclonal RB41406 unconjugated

anti-Signal Transducer and Activator of Transcription 1, 91kDa (STAT1) (AA 1-712) antibody
STAT1 适用: 人 WB, PLA 宿主: 兔 Polyclonal unconjugated

anti-Signal Transducer and Activator of Transcription 1, 91kDa (STAT1) (AA 650-750) antibody
STAT1 适用: 人 WB, IHC, IP, IF 宿主: 兔 Polyclonal unconjugated

anti-Signal Transducer and Activator of Transcription 1, 91kDa (STAT1) (AA 513-712) antibody
STAT1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Signal Transducer and Activator of Transcription 1, 91kDa (STAT1) (AA 1-712) antibody
STAT1 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated

anti-Signal Transducer and Activator of Transcription 1, 91kDa (STAT1) (AA 613-712) antibody
STAT1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 1A8 unconjugated

应用备注

Optimal working dilutions should be determined experimentally by the investigator.

说明

Antigen size: 750 AA

限制

仅限研究用
状态

Liquid

浓度

Lot specific

缓冲液

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freeze-thaw cycles.

储存条件

-20 °C

储存方法

For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Deng, Chen, Li, Liu, Niu, Zhou, Li, Ke, Mo et al.: "Bone marrow mesenchymal stromal cells with support of bispecific antibody and ultrasound-mediated microbubbles prevent myocardial fibrosis via the signal transducer and activators of transcription ..." in: Cytotherapy, Vol. 13, Issue 4, pp. 431-40, (2011) (PubMed).
抗原

STAT1 (Signal Transducer and Activator of Transcription 1, 91kDa (STAT1))

别名

STAT1 (STAT1 产品)

别名

CANDF7 antibody, ISGF-3 antibody, STAT91 antibody, 2010005J02Rik antibody, AA408197 antibody, XStat1 antibody, STAT4 antibody, DD6G4-4 antibody, STAT antibody, STAT1 antibody, dZ182H3.3 antibody, si:by134g18.2 antibody, si:by51f19.1 antibody, si:dz182h3.3 antibody, si:dz199m19.1 antibody, si:dz73o4.2 antibody, stat1 antibody, signal transducer and activator of transcription 1 antibody, signal transducer and activator of transcription 1 L homeolog antibody, signal transducer and activator of transcription 1, 91kDa antibody, signal transducer and activator of transcription 4 antibody, signal transducer and activator of transcription 1a antibody, STAT1 antibody, Stat1 antibody, stat1.L antibody, stat4 antibody, stat1a antibody

背景

STAT1 is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein can be activated by various ligands including interferon-alpha, interferon-gamma, EGF, PDGF and IL6. This protein mediates the expression of a variety of genes, which is thought to be important for cell viability in response to different cell stimuli and pathogens.The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein can be activated by various ligands including interferon-alpha, interferon-gamma, EGF, PDGF and IL6. This protein mediates the expression of a variety of genes, which is thought to be important for cell viability in response to different cell stimuli and pathogens. Two alternatively spliced transcript variants encoding distinct isoforms have been described.
Alias Symbols: DKFZp686B04100, ISGF-3, STAT91, CANDF7
Protein Interaction Partner: HUWE1, ISG15, PIAS1, UBC, STAT1, EIF1AD, OTUD4, LMO2, GNB2, DTX3L, EGFR, NAA15, SNX6, CAND1, VPS29, GSPT2, JMJD6, RTF1, HSPA4L, ATG7, YAP1, PAWR, KARS, IDE, CTTN, VPS26A, HIRIP3, NAA10, TSNAX, TBCD, SNX2, SNX1, SHMT2, SHMT1, SARS, ATP6V1C1, APEH, USP13, E
Protein Size: 750

分子量

87 kDa

基因ID

6772

NCBI登录号

NM_007315, NP_009330

UniProt

P42224

途径

JAK/STAT Signaling, RTK signaling, Interferon-gamma Pathway, Response to Growth Hormone Stimulus, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Endopeptidase Activity, Hepatitis C, CXCR4-mediated Signaling Events