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SOX6 抗体 (Middle Region)

SOX6 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2777776
发货至: 中国
  • 抗原 See all SOX6 抗体
    SOX6 (SRY (Sex Determining Region Y)-Box 6 (SOX6))
    抗原表位
    • 16
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    适用
    • 46
    • 17
    • 16
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔, 斑马鱼
    宿主
    • 41
    • 5
    克隆类型
    • 44
    • 2
    多克隆
    标记
    • 24
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SOX6 antibody is un-conjugated
    应用范围
    • 22
    • 14
    • 13
    • 13
    • 11
    • 5
    • 5
    • 5
    • 4
    • 3
    • 3
    • 2
    • 1
    Western Blotting (WB)
    序列
    YGMKTDGGSL AGNEMINGED EMEMYDDYED DPKSDYSSEN EAPEAVSAN
    预测反应
    Cow: 100%, Dog: 93%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 79%
    产品特性
    This is a rabbit polyclonal antibody against SOX6. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the middle region of human SOX6
    Top Product
    Discover our top product SOX6 Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 804 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    SOX6 (SRY (Sex Determining Region Y)-Box 6 (SOX6))
    别名
    SOX6 (SOX6 产品)
    别名
    HSSOX6 antibody, SOXD antibody, Sox6 antibody, AI987981 antibody, SOX-LZ antibody, fc35a10 antibody, fc50e03 antibody, sox-lz antibody, sox6b antibody, wu:fc35a10 antibody, wu:fc50e03 antibody, SRY-box 6 antibody, SRY box 6 antibody, SRY (sex determining region Y)-box 6 antibody, SOX6 antibody, Sox6 antibody, sox6 antibody
    背景
    SOX6 is a member of the D subfamily of sex determining region y-related transcription factors that are characterized by a conserved DNA-binding domain termed the high mobility group box and by their ability to bind the minor groove of DNA. SOX6 is a transcriptional activator that is required for normal development of the central nervous system, chondrogenesis and maintenance of cardiac and skeletal muscle cells. SOX6 interacts with other family members to cooperatively activate gene expression.Members of the SOX gene family, such as SOX6, encode transcription factors defined by the conserved high mobility group (HMG) DNA-binding domain. Unlike most transcription factors, SOX transcription factors bind to the minor groove of DNA, causing a 70- to 85-degree bend and introducing local conformational changes (Cohen-Barak et al., 2001 [PubMed 11255018]).[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-2696 AL136780.1 1-2696 2697-5158 AC009869.7 10394-12855
    Alias Symbols: HSSOX6, SOXD
    Protein Interaction Partner: TAF4, TRIP12, UBC, SOX2, POMGNT1, ZNF184, UBE2J1, SUMO1, SUMO2, SUMO3, HDAC1, CTNNB1, SOX5, CENPK, DAZAP2, SOX6, CTBP2,
    Protein Size: 804
    分子量
    89 kDa
    基因ID
    55553
    NCBI登录号
    NM_017508, NP_059978
    UniProt
    A8MRT1
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