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RIPK3 抗体 (N-Term)

RIPK3 适用: 人, 小鼠, 大鼠, Cow, 马 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2777619
发货至: 中国
  • 抗原 See all RIPK3 抗体
    RIPK3 (Receptor-Interacting serine-threonine Kinase 3 (RIPK3))
    抗原表位
    • 11
    • 8
    • 8
    • 8
    • 7
    • 5
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    • 80
    • 41
    • 19
    • 6
    • 4
    • 4
    • 2
    • 1
    人, 小鼠, 大鼠, Cow, 马
    宿主
    • 81
    • 9
    克隆类型
    • 81
    • 9
    多克隆
    标记
    • 45
    • 9
    • 8
    • 7
    • 5
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This RIPK3 antibody is un-conjugated
    应用范围
    • 83
    • 52
    • 44
    • 19
    • 11
    • 8
    • 5
    • 5
    • 4
    • 2
    • 1
    Western Blotting (WB)
    序列
    AQHRKWGYDV AVKIVNSKAI SREVKAMASL DNEFVLRLEG VIEKVNWDQD
    预测反应
    Cow: 93%, Horse: 86%, Human: 100%, Mouse: 86%, Rat: 93%
    产品特性
    This is a rabbit polyclonal antibody against RIPK3. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the N terminal region of human RIPK3
    Top Product
    Discover our top product RIPK3 Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 518 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    RIPK3 (Receptor-Interacting serine-threonine Kinase 3 (RIPK3))
    别名
    RIPK3 (RIPK3 产品)
    别名
    RIPK3 antibody, RIP3 antibody, 2610528K09Rik antibody, AW107945 antibody, Rip3 antibody, Hcyp2 antibody, receptor interacting serine/threonine kinase 3 antibody, receptor interacting serine/threonine kinase 3 S homeolog antibody, receptor-interacting serine-threonine kinase 3 antibody, RIPK3 antibody, ripk3.S antibody, Ripk3 antibody
    背景
    RIPK3 is a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases, and contains a C-terminal domain unique from other RIP family members. The protein is predominantly localized to the cytoplasm, and can undergo nucleocytoplasmic shuttling dependent on novel nuclear localization and export signals. It is a component of the tumor necrosis factor (TNF) receptor-I signaling complex, and can induce apoptosis and weakly activate the NF-kappaB transcription factor. The product of this gene is a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases, and contains a C-terminal domain unique from other RIP family members. The encoded protein is predominantly localized to the cytoplasm, and can undergo nucleocytoplasmic shuttling dependent on novel nuclear localization and export signals. It is a component of the tumor necrosis factor (TNF) receptor-I signaling complex, and can induce apoptosis and weakly activate the NF-kappaB transcription factor. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    Alias Symbols: RIP3
    Protein Interaction Partner: BMH1, RFX6, FADD, RIPK1, CASP8, INPP5K, CDC37, STIP1, PYGL, FKBP5, FKBP4, CTNND1, UBC, XIAP, BIRC3, BIRC2, TICAM1, TRAF2, TNFRSF1A,
    Protein Size: 518
    分子量
    57 kDa
    基因ID
    11035
    NCBI登录号
    NM_006871, NP_006862
    UniProt
    Q9Y572
    途径
    Activation of Innate immune Response, Toll-Like Receptors Cascades
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