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Medium-Chain Specific Acyl-CoA Dehydrogenase, Mitochondrial (N-Term) 抗体

适用: 人, 小鼠, 大鼠, Cow, 马 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2777593
发货至: 中国
  • 抗原
    Medium-Chain Specific Acyl-CoA Dehydrogenase, Mitochondrial
    抗原表位
    • 15
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    • 53
    • 19
    • 16
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠, Cow, 马
    宿主
    • 47
    • 4
    • 2
    克隆类型
    • 48
    • 4
    多克隆
    标记
    • 27
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    非结合性
    应用范围
    • 25
    • 15
    • 14
    • 13
    • 12
    • 11
    • 8
    • 4
    • 4
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB)
    序列
    AAGFGRCCRV LRSISRFHWR SQHTKANRQR EPGLGFSFEF TEQQKEFQAT
    预测反应
    Cow: 92%, Horse: 92%, Human: 100%, Mouse: 91%, Rat: 91%
    产品特性
    This is a rabbit polyclonal antibody against ACADM. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the N terminal region of human ACADM
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 421 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    Medium-Chain Specific Acyl-CoA Dehydrogenase, Mitochondrial
    别名
    ACADM
    别名
    ACAD1 antibody, MCAD antibody, MCADH antibody, AU018656 antibody, acyl-CoA dehydrogenase medium chain antibody, acyl-Coenzyme A dehydrogenase, medium chain antibody, acyl-CoA dehydrogenase, C-4 to C-12 straight chain antibody, ACADM antibody, Acadm antibody
    背景
    ACADM Is the medium-chain specific (C4 to C12 straight chain) acyl-Coenzyme A dehydrogenase. The homotetramer enzyme catalyzes the initial step of the mitochondrial fatty acid beta-oxidation pathway. Clinical phenotypes are associated with ACADM hereditary deficiency.This gene encodes the medium-chain specific (C4 to C12 straight chain) acyl-Coenzyme A dehydrogenase. The homotetramer enzyme catalyzes the initial step of the mitochondrial fatty acid beta-oxidation pathway. Defects in this gene cause medium-chain acyl-CoA dehydrogenase deficiency, a disease characterized by hepatic dysfunction, fasting hypoglycemia, and encephalopathy, which can result in infantile death. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
    Alias Symbols: ACAD1, MCAD, MCADH
    Protein Interaction Partner: SUMO2, SUMO3, UBC, MDM2, STRAP, HDAC1, UBD, CUL3, SUMO4, CALM1, USP50, USP20, ACADM,
    Protein Size: 421
    分子量
    46 kDa
    基因ID
    34
    NCBI登录号
    NM_000016, NP_000007
    UniProt
    P11310
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