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PDPK1 抗体 (Middle Region)

PDPK1 适用: 人, 小鼠, 大鼠, Cow, 兔, 犬, 豚鼠, 马, Saccharomyces cerevisiae WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2777432
发货至: 中国
  • 抗原 See all PDPK1 抗体
    PDPK1 (3-phosphoinositide Dependent Protein Kinase-1 (PDPK1))
    抗原表位
    • 23
    • 19
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    • 15
    • 9
    • 7
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    Middle Region
    适用
    • 181
    • 116
    • 80
    • 11
    • 5
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠, Cow, 兔, 犬, 豚鼠, 马, Saccharomyces cerevisiae
    宿主
    • 179
    • 18
    • 1
    克隆类型
    • 166
    • 32
    多克隆
    标记
    • 88
    • 12
    • 10
    • 9
    • 7
    • 7
    • 7
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    • 7
    • 5
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    • 5
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    • 2
    This PDPK1 antibody is un-conjugated
    应用范围
    • 153
    • 70
    • 53
    • 53
    • 27
    • 27
    • 12
    • 11
    • 10
    • 8
    • 8
    • 8
    • 3
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    Western Blotting (WB)
    序列
    ATMEHHANRG VYPPIQVHVT LGNEDLTVKM SDRGGGVPLR KIDRLFNYMY
    预测反应
    Cow: 86%, Dog: 79%, Guinea Pig: 86%, Horse: 86%, Human: 100%, Mouse: 86%, Rabbit: 86%, Rat: 86%, Yeast: 90%
    产品特性
    This is a rabbit polyclonal antibody against PDK1. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the middle region of human PDK1
    Top Product
    Discover our top product PDPK1 Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 436 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    PDPK1 (3-phosphoinositide Dependent Protein Kinase-1 (PDPK1))
    别名
    PDK1 (PDPK1 产品)
    别名
    pdpk1 antibody, MGC82080 antibody, PDK1 antibody, PDPK2 antibody, PRO0461 antibody, Pdk1 antibody, zgc:153787 antibody, 3'-phosphoinositide-dependent protein kinase 1 antibody, 3-PHOSPHOINOSITIDE-DEPENDENT PROTEIN KINASE 1 antibody, ATPDK1 antibody, AtPDK1 antibody, T32M21.110 antibody, T32M21_110 antibody, zgc:77318 antibody, 3-phosphoinositide dependent protein kinase 1 antibody, 3-phosphoinositide dependent protein kinase 1 L homeolog antibody, 3-phosphoinositide dependent protein kinase-1 antibody, 3-phosphoinositide dependent protein kinase 1a antibody, 3-phosphoinositide-dependent protein kinase 1 antibody, 3'-phosphoinositide-dependent protein kinase 1 antibody, 3-phosphoinositide dependent protein kinase 1b antibody, PDPK1 antibody, pdpk1.L antibody, pdpk1 antibody, Pdpk1 antibody, pdpk1a antibody, LOC100380750 antibody, pdk-1 antibody, PDK1 antibody, pdpk1b antibody
    背景
    Pyruvate dehydrogenase (PDH) is a mitochondrial multienzyme complex that catalyzes the oxidative decarboxylation of pyruvate and is one of the major enzymes responsible for the regulation of homeostasis of carbohydrate fuels in mammals. The enzymatic activity is regulated by a phosphorylation/dephosphorylation cycle. Phosphorylation of PDH by a specific pyruvate dehydrogenase kinase (PDK) results in inactivation.Pyruvate dehydrogenase (PDH) is a mitochondrial multienzyme complex that catalyzes the oxidative decarboxylation of pyruvate and is one of the major enzymes responsible for the regulation of homeostasis of carbohydrate fuels in mammals. The enzymatic activity is regulated by a phosphorylation/dephosphorylation cycle. Phosphorylation of PDH by a specific pyruvate dehydrogenase kinase (PDK) results in inactivation. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    Alias Symbols: -
    Protein Interaction Partner: EGFR, PDK1, KAT2B, USP4, UBC, MYC, XRCC6, SGK1, DLAT, RPS6KB1, PDK2, PDHA1, YWHAQ, RPTOR, RALGDS, PKN2, PKN1, MTOR, AKT1,
    Protein Size: 436
    分子量
    47 kDa
    基因ID
    5163
    NCBI登录号
    NM_002610, NP_002601
    UniProt
    Q15118
    途径
    PI3K-Akt Signaling, TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cell-Cell Junction Organization, Regulation of Cell Size, Skeletal Muscle Fiber Development, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, VEGFR1 Specific Signals
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