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ERCC8 抗体 (C-Term)

ERCC8 适用: 人, 大鼠, 犬, 兔, 马, Pig WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2777347
发货至: 中国
  • 抗原 See all ERCC8 抗体
    ERCC8 (Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 8 (ERCC8))
    抗原表位
    • 15
    • 8
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 46
    • 32
    • 21
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    人, 大鼠, 犬, 兔, 马, Pig
    宿主
    • 40
    • 6
    克隆类型
    • 42
    • 4
    多克隆
    标记
    • 27
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ERCC8 antibody is un-conjugated
    应用范围
    • 46
    • 13
    • 13
    • 10
    • 9
    • 8
    • 7
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    序列
    QELYSGSRDC NILAWVPSLY EPVPDDDETT TKSQLNPAFE DAWSSSDEEG
    预测反应
    Dog: 93%, Horse: 86%, Human: 100%, Pig: 79%, Rabbit: 79%, Rat: 79%
    产品特性
    This is a rabbit polyclonal antibody against ERCC8. It was validated on Western Blot and immunohistochemistry.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the C terminal region of human ERCC8
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 396 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Fleury, Carmona, Morin, Meunier, Masson, Tonin, Provencher, Mes-Masson: "Cumulative defects in DNA repair pathways drive the PARP inhibitor response in high-grade serous epithelial ovarian cancer cell lines." in: Oncotarget, Vol. 8, Issue 25, pp. 40152-40168, (2018) (PubMed).

  • 抗原
    ERCC8 (Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 8 (ERCC8))
    别名
    ERCC8 (ERCC8 产品)
    别名
    zgc:103550 antibody, CKN1 antibody, CSA antibody, UVSS2 antibody, Ckn1 antibody, 2410022P04Rik antibody, 2810431L23Rik antibody, 4631412O06Rik antibody, B130065P18Rik antibody, Csa antibody, excision repair cross-complementation group 8 antibody, ERCC excision repair 8, CSA ubiquitin ligase complex subunit antibody, excision repaiross-complementing rodent repair deficiency, complementation group 8 antibody, ercc8 antibody, ERCC8 antibody, Ercc8 antibody
    背景
    ERCC8 (excision repair cross-complementing rodent repair deficiency, complementation group 8 isoform 1) is a WD repeat protein, which interacts with Cockayne syndrome type B (CSB) protein and with p44 protein, a subunit of the RNA polymerase II transcript
    Alias Symbols: CKN1, CSA
    Protein Interaction Partner: CUL4A, CUL4B, DDB1, RUVBL2, ZNF24, PCNA, H1F0, ERCC6, UVSSA, DDA1, RFWD2, COPS4, COPS6, COPS3, TOP1, TP53, SSBP1, OGG1, MDM2, GTF2H2, CUL5, GPS1, DDB2, COPS2, COPS7A, COPS5, COPS8, RBX1, POLR2A, HMGN1, EP300, UBC, CSNK2B, XAB2, UQCRQ, CBR1,
    Protein Size: 396
    分子量
    44 kDa
    基因ID
    1161
    NCBI登录号
    NM_000082, NP_000073
    UniProt
    Q13216
    途径
    DNA Damage Repair, Positive Regulation of Response to DNA Damage Stimulus
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