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POU1F1 抗体 (N-Term)

POU1F1 适用: 人, 小鼠, 大鼠, 犬, Cow, 山羊, 马, 兔, 绵羊, 豚鼠, Pig WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2777284
发货至: 中国
  • 抗原 See all POU1F1 抗体
    POU1F1 (POU Class 1 Homeobox 1 (POU1F1))
    抗原表位
    • 2
    • 1
    • 1
    N-Term
    适用
    • 9
    • 6
    • 6
    • 6
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    人, 小鼠, 大鼠, 犬, Cow, 山羊, 马, 兔, 绵羊, 豚鼠, Pig
    宿主
    • 9
    克隆类型
    • 9
    多克隆
    标记
    • 9
    This POU1F1 antibody is un-conjugated
    应用范围
    • 7
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB)
    序列
    TPCLYKFPDH TLSHGFPPIH QPLLAEDPTA ADFKQELRRK SKLVEEPIDM
    预测反应
    Cow: 100%, Dog: 92%, Goat: 100%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 86%, Pig: 100%, Rabbit: 100%, Rat: 86%, Sheep: 100%
    产品特性
    This is a rabbit polyclonal antibody against POU1F1. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Protein A purified
    免疫原
    The immunogen is a synthetic peptide directed towards the N terminal region of human POU1F1
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 291 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Dattani: "Borjeson-Forssman-Lehmann syndrome: a novel pituitary phenotype due to mutation in a novel gene." in: Journal of pediatric endocrinology & metabolism : JPEM, Vol. 16, Issue 9, pp. 1207-9, (2004) (PubMed).

  • 抗原
    POU1F1 (POU Class 1 Homeobox 1 (POU1F1))
    别名
    POU1F1 (POU1F1 产品)
    别名
    CPHD1 antibody, GHF-1 antibody, PIT1 antibody, POU1F1a antibody, Pit-1 antibody, Hmp1 antibody, Pit1 antibody, Pit1-rs1 antibody, dw antibody, dwarf antibody, GHF1 antibody, GHF1A antibody, PIT1Z antibody, PIT-1 antibody, Pit-1* antibody, pit1 antibody, pit-1 antibody, POU class 1 homeobox 1 antibody, POU domain, class 1, transcription factor 1 antibody, POU1F1 antibody, Pou1f1 antibody, pou1f1 antibody
    背景
    PIT1 is a pituitary-specific transcription factor responsible for pituitary development and hormone expression in mammals and is a member of the POU family of transcription factors that regulate mammalian development. The POU family is so named because the first 3 members identified were PIT1 and OCT1 of mammals, and Unc-86 of C. elegans. PIT1 contains 2 protein domains, termed POU-specific and POU-homeo, which are both necessary for high affinity DNA binding on genes encoding growth hormone and prolactin. PIT1 is also important for regulation of the genes encoding prolactin and thyroid-stimulating hormone beta subunit by thyrotropin-releasing hormone and cyclic AMP.
    Alias Symbols: PIT1, CPHD1, GHF-1, Pit-1, POU1F1a
    Protein Interaction Partner: CEBPD, NCOR1, CREBBP, MED1, GATA2, NR1I3, NR1I2, PITX1, JUN, ETS1, NR3C1, VDR, PPARG, PPARA,
    Protein Size: 291
    分子量
    33 kDa
    基因ID
    5449
    NCBI登录号
    NM_000306, NP_000297
    UniProt
    P28069
    途径
    Regulation of Carbohydrate Metabolic Process
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