BDNF 抗体 (Middle Region)
(6 references)-
- 抗原 See all BDNF 抗体
- BDNF (Brain-Derived Neurotrophic Factor (BDNF))
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抗原表位
- Middle Region
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适用
- 人, 大鼠, 小鼠, Pig, 兔, 马, 犬
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This BDNF antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC)
- 序列
- EWVTAADKKT AVDMSGGTVT VLEKVPVSKG QLKQYFYETK CNPMGYTKEG
- 预测反应
- Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%
- 产品特性
- This is a rabbit polyclonal antibody against BDNF. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human BDNF
- Top Product
- Discover our top product BDNF Primary Antibody
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anti-Brain-Derived Neurotrophic Factor (BDNF) (AA 20-252) antibody
BDNF 适用: Pig WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Brain-Derived Neurotrophic Factor (BDNF) (AA 19-248) antibodyBDNF 适用: 人 WB, ELISA, ICC 宿主: 小鼠 Monoclonal 3D9C5 unconjugated
anti-Brain-Derived Neurotrophic Factor (BDNF) (AA 151-247) antibodyBDNF 适用: 人, 大鼠, 小鼠 WB, ELISA, ICC, IF (cc), IF (p), FACS, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Brain-Derived Neurotrophic Factor (BDNF) (AA 20-252) antibodyBDNF 适用: Pig WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C1 unconjugated
anti-Brain-Derived Neurotrophic Factor (BDNF) (AA 1-247) antibodyBDNF 适用: 人 WB, ELISA, IP, IF 宿主: 小鼠 Monoclonal 1B10 unconjugated
anti-Brain-Derived Neurotrophic Factor (BDNF) (Internal Region) antibodyVerified BDNF 适用: 人 ELISA, IF 宿主: 山羊 Polyclonal unconjugated
anti-Brain-Derived Neurotrophic Factor (BDNF) (AA 129-247) antibodyBDNF 适用: 大鼠, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Brain-Derived Neurotrophic Factor (BDNF) (AA 206-236) antibodyBDNF 适用: 人 WB, IHC, ELISA, IF, FACS 宿主: 兔 Polyclonal unconjugated
anti-Brain-Derived Neurotrophic Factor (BDNF) (AA 129-247) antibodyBDNF 适用: 人, 大鼠, 小鼠 WB, FACS, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Brain-Derived Neurotrophic Factor (BDNF) (AA 20-247) antibodyBDNF 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 247 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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: "Prenatal Cocaine Exposure Alters BDNF-TrkB Signaling in the Embryonic and Adult Brain." in: Developmental neuroscience, Vol. 38, Issue 5, pp. 365-374, (2017) (PubMed).
: "Reversal Learning Deficits Associated with Increased Frontal Cortical Brain-Derived Neurotrophic Factor Tyrosine Kinase B Signaling in a Prenatal Cocaine Exposure Mouse Model." in: Developmental neuroscience, Vol. 38, Issue 5, pp. 354-364, (2016) (PubMed).
: "Sex differences and estrogen regulation of BDNF gene expression, but not propeptide content, in the developing hippocampus." in: Journal of neuroscience research, Vol. 95, Issue 1-2, pp. 345-354, (2016) (PubMed).
: "TrkB/BDNF signalling patterns the sympathetic nervous system." in: Nature communications, Vol. 6, pp. 8281, (2015) (PubMed).
: "Epigenetic inheritance of a cocaine-resistance phenotype." in: Nature neuroscience, Vol. 16, Issue 1, pp. 42-7, (2012) (PubMed).
: "Cocaine alters BDNF expression and neuronal migration in the embryonic mouse forebrain." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 31, Issue 38, pp. 13400-11, (2011) (PubMed).
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: "Prenatal Cocaine Exposure Alters BDNF-TrkB Signaling in the Embryonic and Adult Brain." in: Developmental neuroscience, Vol. 38, Issue 5, pp. 365-374, (2017) (PubMed).
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- 抗原
- BDNF (Brain-Derived Neurotrophic Factor (BDNF))
- 别名
- BDNF (BDNF 产品)
- 别名
- ANON2 antibody, BULN2 antibody, bdnf-A antibody, BDNF antibody, bdnf antibody, brain derived neurotrophic factor antibody, brain-derived neurotrophic factor antibody, brain-derived neurotrophic factor L homeolog antibody, brain-derived neurotrophic factor S homeolog antibody, BDNF antibody, Bdnf antibody, bdnf antibody, bdnf.L antibody, bdnf.S antibody
- 背景
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BDNF is a member of the nerve growth factor family. It is induced by cortical neurons, and is necessary for survival of striatal neurons in the brain. Expression BDNF is reduced in both Alzheimer's and Huntington disease patients. BDNF may play a role in the regulation of stress response and in the biology of mood disorders.The protein encoded by this gene is a member of the nerve growth factor family. It is induced by cortical neurons, and is necessary for survival of striatal neurons in the brain. Expression of this gene is reduced in both Alzheimer's and Huntington disease patients. This gene may play a role in the regulation of stress response and in the biology of mood disorders. Multiple transcript variants encoding distinct isoforms have been described for this gene, but the full-length nature of only some could be determined.
Alias Symbols: MGC34632
Protein Interaction Partner: UBC, AGO3, INPP5K, F11R, JUNB, APP, ELAVL1, Ntrk2, CADPS2, MBTPS1, SORT1, NOS3, NTF4, NTF3, ESR1, NCAM1, CPE, BDNF,
Protein Size: 247 - 分子量
- 27 kDa
- 基因ID
- 627
- NCBI登录号
- NM_001709, NP_001700
- UniProt
- P23560
- 途径
- RTK signaling, Synaptic Membrane, Feeding Behaviour, Dicarboxylic Acid Transport, Regulation of long-term Neuronal Synaptic Plasticity
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