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Leptin 抗体 (Middle Region)

LEP 适用: 人, 小鼠, 大鼠, Cow, 马, 犬, 山羊, 兔, 绵羊, Pig WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2776944
发货至: 中国
  • 抗原 See all Leptin (LEP) 抗体
    Leptin (LEP)
    抗原表位
    • 25
    • 16
    • 15
    • 15
    • 12
    • 11
    • 10
    • 7
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    适用
    • 119
    • 72
    • 70
    • 11
    • 7
    • 6
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    人, 小鼠, 大鼠, Cow, 马, 犬, 山羊, 兔, 绵羊, Pig
    宿主
    • 168
    • 23
    • 6
    • 5
    • 2
    克隆类型
    • 179
    • 24
    多克隆
    标记
    • 100
    • 26
    • 17
    • 9
    • 8
    • 7
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    This Leptin antibody is un-conjugated
    应用范围
    • 132
    • 85
    • 63
    • 39
    • 39
    • 38
    • 32
    • 30
    • 25
    • 21
    • 16
    • 11
    • 11
    • 6
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    序列
    LHVLAFSKSC HLPWASGLET LDSLGGVLEA SGYSTEVVAL SRLQGSLQDM
    预测反应
    Cow: 100%, Dog: 86%, Goat: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 93%, Rabbit: 93%, Rat: 100%, Sheep: 100%
    产品特性
    This is a rabbit polyclonal antibody against LEP. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the middle region of human LEP
    Top Product
    Discover our top product LEP Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 167 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    Leptin (LEP)
    别名
    LEP (LEP 产品)
    别名
    ob antibody, obese antibody, LEPD antibody, OB antibody, OBS antibody, leptin antibody, Lep antibody, LEP antibody, lep antibody
    背景
    LEP is a protein that is secreted by white adipocytes, and which plays a major role in the regulation of body weight. This protein, which acts through the leptin receptor, functions as part of a signaling pathway that can inhibit food intake and/or regulate energy expenditure to maintain constancy of the adipose mass. This protein also has several endocrine functions, and is involved in the regulation of immune and inflammatory responses, hematopoiesis, angiogenesis and wound healing. Mutations in this gene and/or its regulatory regions cause severe obesity, and morbid obesity with hypogonadism. This gene has also been linked to type 2 diabetes mellitus development.This gene encodes a protein that is secreted by white adipocytes, and which plays a major role in the regulation of body weight. This protein, which acts through the leptin receptor, functions as part of a signaling pathway that can inhibit food intake and/or regulate energy expenditure to maintain constancy of the adipose mass. This protein also has several endocrine functions, and is involved in the regulation of immune and inflammatory responses, hematopoiesis, angiogenesis and wound healing. Mutations in this gene and/or its regulatory regions cause severe obesity, and morbid obesity with hypogonadism. This gene has also been linked to type 2 diabetes mellitus development. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    Alias Symbols: OB, OBS
    Protein Interaction Partner: Hk3, SIGLEC6, GHRL, LEPR, UCN, PRKAA2, CLU, CRP, A2M, STAT3,
    Protein Size: 167
    分子量
    16 kDa
    基因ID
    3952
    NCBI登录号
    NM_000230, NP_000221
    UniProt
    P41159
    途径
    JAK/STAT Signaling, AMPK Signaling, Hormone Transport, Peptide Hormone Metabolism, Hormone Activity, Negative Regulation of Hormone Secretion, Regulation of Carbohydrate Metabolic Process, Feeding Behaviour, Monocarboxylic Acid Catabolic Process
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