SRSF10 抗体 (serine/arginine-Rich Splicing Factor 10) (C-Term)

Details for Product anti-SRSF10 Antibody No. ABIN2776611, 供应商: Log in to see
抗原
  • FUSIP1
  • SFRS13A
  • FUSIP2
  • NSSR
  • SFRS13
  • SRp38
  • SRrp40
  • TASR
  • TASR1
  • TASR2
  • Fusip1
  • NSSR1
  • NSSR2
  • Nssr
  • Sfrs13a
  • Srsf13a
  • fusip1
  • fusip2
  • nssr
  • sfrs13
  • sfrs13a
  • srp38
  • srrp40
  • tasr
  • tasr1
  • tasr2
  • serine/arginine-rich splicing factor 10
  • splicing factor, arginine/serine-rich 13A
  • SRSF10
  • Srsf10
  • srsf10
  • SFRS13A
抗原表位
C-Term
14
13
10
4
4
4
3
3
2
2
1
1
1
适用
豚鼠, 马, 人, 小鼠, 兔, 大鼠
70
32
22
5
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3
3
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1
1
宿主

57
13
克隆类型
多克隆
标记
This SRSF10 antibody is un-conjugated
5
4
4
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3
1
1
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1
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1
应用范围
Immunohistochemistry (IHC), Western Blotting (WB)
53
28
13
13
11
10
9
3
选项
Supplier
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Supplier Product No.
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免疫原 The immunogen is a synthetic peptide directed towards the C terminal region of human FUSIP1
Blocking Peptide Blocking peptide for this product available: ABIN977144
序列 TDSKTHYKSG SRYEKESRKK EPPRSKSQSR SQSRSRSKSR SRSWTSPKSS
预测反应 Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
产品特性 This is a rabbit polyclonal antibody against FUSIP1. It was validated on Western Blot and immunohistochemistry.
纯化方法 Affinity Purified
别名 FUSIP1 (SRSF10 Antibody 摘要)
背景 FUSIP1 is a member of the serine-arginine (SR) family of proteins, which is involved in constitutive and regulated RNA splicing. Members of this family are characterized by N-terminal RNP1 and RNP2 motifs, which are required for binding to RNA, and multiple C-terminal SR/RS repeats, which are important in mediating association with other cellular proteins. This protein can influence splice site selection of adenovirus E1A pre-mRNA. It interacts with the oncoprotein TLS, and abrogates the influence of TLS on E1A pre-mRNA splicing.This gene product is a member of the serine-arginine (SR) family of proteins, which is involved in constitutive and regulated RNA splicing. Members of this family are characterized by N-terminal RNP1 and RNP2 motifs, which are required for binding to RNA, and multiple C-terminal SR/RS repeats, which are important in mediating association with other cellular proteins. This protein can influence splice site selection of adenovirus E1A pre-mRNA. It interacts with the oncoprotein TLS, and abrogates the influence of TLS on E1A pre-mRNA splicing. Alternative splicing of this gene results in at least two transcript variants encoding different isoforms. In addition, transcript variants utilizing alternative polyA sites exist.
Alias Symbols: FUSIP2, NSSR, SFRS13, SRp38, SRrp40, TASR, TASR1, TASR2, FUSIP1, SFRS13A
Protein Interaction Partner: STAU1, WWOX, SUZ12, EED, RNF2, EZH2, HECW2, TRA2B, SRSF4, SRSF1, CSNK2A1, EIF4A3, MAGOH, PAXIP1, BARD1, SAP18, VTN, TCOF1, SRSF6, S100A9, PRKDC, NHP2L1, NFIA, SEPT2, MSH2, IK, EPRS, DHX15, BCAS2, TRIM55, THOC6, ZNF687, SMU1, TRMT112, TRA2A, PHGDH, NCSTN,
Protein Size: 262
分子量 29 kDa
基因ID 10772
NCBI登录号 NM_054016, NP_473357
UniProt O75494
研究领域 Chromatin and Nuclear Signaling, DNA/RNA
途径 Ribonucleoprotein Complex Subunit Organization
应用备注 Optimal working dilutions should be determined experimentally by the investigator.
说明

Antigen size: 262 AA

限制 仅限研究用
状态 Liquid
浓度 Lot specific
缓冲液 Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
储存液 Sodium azide
注意事项 This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
注意事项 Avoid repeated freeze-thaw cycles.
储存条件 -20 °C
储存方法 For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
厂商提供的图像
Western Blotting (WB) image for anti-serine/arginine-Rich Splicing Factor 10 (SRSF10) (C-Term) antibody (ABIN2776611) WB Suggested Anti-FUSIP1 Antibody Titration: 0.2-1 ug/ml
Positive Contro...
Immunohistochemistry (IHC) image for anti-serine/arginine-Rich Splicing Factor 10 (SRSF10) (C-Term) antibody (ABIN2776611) anti-serine/arginine-Rich Splicing Factor 10 (SRSF10) (C-Term) antibody (Image 2)
Western Blotting (WB) image for anti-serine/arginine-Rich Splicing Factor 10 (SRSF10) (C-Term) antibody (ABIN2776611) WB Suggested Anti-FUSIP1
Antibody Titration: 0.2-1 µg/mL
Positive Contr...
背景 Shin, Kleiman, Manley: "Multiple properties of the splicing repressor SRp38 distinguish it from typical SR proteins." in: Molecular and cellular biology, Vol. 25, Issue 18, pp. 8334-43, 2005 (PubMed).

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