TRPM8 抗体 (N-Term)
-
- 抗原 See all TRPM8 抗体
- TRPM8 (Transient Receptor Potential Cation Channel, Subfamily M, Member 8 (TRPM8))
-
抗原表位
- N-Term
-
适用
- 人, 大鼠, 小鼠, 豚鼠, 犬, 兔, 马, Cow, Pig
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This TRPM8 antibody is un-conjugated
-
应用范围
- Western Blotting (WB), Immunohistochemistry (IHC)
- 序列
- YILDNNHTHL LLVDNGCHGH PTVEAKLRNQ LEKYISERTI QDSNYGGKIP
- 预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 100%, Rat: 93%
- 产品特性
- This is a rabbit polyclonal antibody against TRPM8. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human TRPM8
- Top Product
- Discover our top product TRPM8 Primary Antibody
-
anti-Transient Receptor Potential Cation Channel, Subfamily M, Member 8 (TRPM8) (AA 926-956), (C-Term) antibody
TRPM8 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB14420 unconjugated
anti-Transient Receptor Potential Cation Channel, Subfamily M, Member 8 (TRPM8) (AA 521-552) antibodyTRPM8 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Transient Receptor Potential Cation Channel, Subfamily M, Member 8 (TRPM8) (AA 263-292) antibodyTRPM8 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Transient Receptor Potential Cation Channel, Subfamily M, Member 8 (TRPM8) (3rd Extracellular Loop), (AA 917-929) antibodyTRPM8 适用: 人, 大鼠, 小鼠 WB, IHC, IF, ICC, IP, LCI, Neut 宿主: 兔 Polyclonal unconjugated
anti-Transient Receptor Potential Cation Channel, Subfamily M, Member 8 (TRPM8) (AA 1-192) antibodyTRPM8 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Transient Receptor Potential Cation Channel, Subfamily M, Member 8 (TRPM8) (N-Term) antibodyTRPM8 适用: 人, 豚鼠, 犬, 兔, Bat, 猴, Hamster IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Transient Receptor Potential Cation Channel, Subfamily M, Member 8 (TRPM8) (AA 933-963) antibodyTRPM8 适用: 人 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Transient Receptor Potential Cation Channel, Subfamily M, Member 8 (TRPM8) (AA 980-1104) antibodyTRPM8 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Transient Receptor Potential Cation Channel, Subfamily M, Member 8 (TRPM8) (Internal Region) antibodyTRPM8 适用: 人, 大鼠, 小鼠, 豚鼠, 猴 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Transient Receptor Potential Cation Channel, Subfamily M, Member 8 (TRPM8) (AA 251-300) antibodyTRPM8 适用: 人, 豚鼠, 犬, 兔, 马, Cow, Pig, Bat, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
-
- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
-
Antigen size: 1104 AA
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
- 抗原
- TRPM8 (Transient Receptor Potential Cation Channel, Subfamily M, Member 8 (TRPM8))
- 别名
- TRPM8 (TRPM8 产品)
- 别名
- TRPM8 antibody, trpp8 antibody, ltrpc6 antibody, trpm8b antibody, LTRPC6 antibody, TRPP8 antibody, CMR1 antibody, LTrpC-6 antibody, Trp-p8 antibody, transient receptor potential cation channel subfamily M member 8 antibody, transient receptor potential cation channel subfamily M member 8b L homeolog antibody, transient receptor potential cation channel, subfamily M, member 8 antibody, TRPM8 antibody, trpm8b.L antibody, Trpm8 antibody
- 背景
-
TRPM8 is the receptor-activated non-selective cation channel involved in detection of sensations such as coolness, by being activated by cold temperature below 25 degrees Celsius. TRPM8 is activated by icilin, eucalyptol, menthol, cold and modulation of intracellular pH . TRPM8 is involved in menthol sensation. TRPM8 is permeable for monovalent cations sodium, potassium, and cesium and divalent cation calcium. Temperature sensing is tightly linked to voltage-dependent gating. TRPM8 was activated upon depolarization, changes in temperature resulting in graded shifts of its voltage-dependent activation curves. The chemical agonists menthol functions as a gating modifier, shifting activation curves towards physiological membrane potentials. Temperature sensitivity arises from a tenfold difference in the activation energies associated with voltage-dependent opening and closing.
Alias Symbols: LTRPC6, MGC2849, TRPP8
Protein Interaction Partner: CHAMP1, TXLNA, ZC3H18, RTF1, SF3A3, USP10,
Protein Size: 1104 - 分子量
- 128 kDa
- 基因ID
- 79054
- NCBI登录号
- NM_024080, NP_076985
- UniProt
- Q7Z2W7
-
