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PAX5 抗体 (Paired Box 5) (N-Term)

Details for Product anti-PAX5 Antibody No. ABIN2775953, 供应商: Log in to see
抗原
  • PAX5
  • BSAP
  • Pax-5
  • pax5-a
  • RGD1565236
  • EBB-1
  • KLP
  • Pax[Zf-b]
  • noi
  • pax2.1
  • pax2a
  • paxzf-b
  • paired box 5
  • paired box gene 5
  • PAX5
  • pax5
  • Pax5
抗原表位
N-Term
26
25
24
14
12
10
9
8
5
4
4
3
2
2
2
2
2
2
2
2
1
1
1
1
适用
牛, 犬, 豚鼠, 马, 人, 小鼠, 兔, 大鼠, 斑马鱼
242
103
28
5
3
2
2
2
2
2
1
1
1
1
宿主

129
62
35
16
克隆类型
多克隆
标记
This PAX5 antibody is un-conjugated
11
10
10
7
6
6
4
4
3
3
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
应用范围
Immunohistochemistry (IHC), Western Blotting (WB)
176
94
84
63
54
21
13
6
6
3
3
2
2
1
1
1
1
Supplier
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免疫原 The immunogen is a synthetic peptide directed towards the N terminal region of human PAX5
Blocking Peptide Blocking peptide for this product available: ABIN981389
序列 CVSKILGRYY ETGSIKPGVI GGSKPKVATP KVVEKIAEYK RQNPTMFAWE
预测反应 Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
产品特性 This is a rabbit polyclonal antibody against PAX5. It was validated on Western Blot and immunohistochemistry.
纯化方法 Affinity Purified
别名 PAX5 (PAX5 Antibody 摘要)
背景 The PAX5 gene is a member of the paired box (PAX) family of transcription factors. The central feature of this gene family is a novel, highly conserved DNA-binding motif, known as the paired box. The PAX proteins are important regulators in early development, and alterations in the expression of their genes are thought to contribute to neoplastic transformation. The PAX5 gene encodes the B-cell lineage specific activator protein (BSAP) that is expressed at early, but not late stages of B-cell differentiation. Its expression has also been detected in developing CNS and testis, therefore, PAX5 gene product may not only play an important role in B-cell differentiation, but also in neural development and spermatogenesis.
Alias Symbols: BSAP
Protein Interaction Partner: TBP, RB1, EP300, RUNX1, TLE4, DAXX, KPNA1, KPNA2, ID2, ID3, CREBBP, MYB, PAX5, ETS1, EBF1,
Protein Size: 391
分子量 42 kDa
基因ID 5079
NCBI登录号 NM_016734, NP_057953
UniProt Q02548
研究领域 Chromatin and Nuclear Signaling, Transcription Factors
应用备注 Optimal working dilutions should be determined experimentally by the investigator.
说明

Antigen size: 391 AA

限制 仅限研究用
状态 Liquid
浓度 Lot specific
缓冲液 Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
储存液 Sodium azide
注意事项 This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
注意事项 Avoid repeated freeze-thaw cycles.
储存条件 -20 °C
储存方法 For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
厂商提供的图像
Western Blotting (WB) image for anti-PAX5 抗体 (Paired Box 5) (N-Term) (ABIN2775953) WB Suggested Anti-PAX5 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: ...
Immunohistochemistry (IHC) image for anti-PAX5 抗体 (Paired Box 5) (N-Term) (ABIN2775953) anti-Paired Box 5 (PAX5) (N-Term) antibody (Image 2)
背景 Robichaud, Nardini, Laflamme, Cuperlovic-Culf, Ouellette: "Human Pax-5 C-terminal isoforms possess distinct transactivation properties and are differentially modulated in normal and malignant B cells." in: The Journal of biological chemistry, Vol. 279, Issue 48, pp. 49956-63, 2004 (PubMed).