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F-Box Protein 11 (FBXO11) (Middle Region) 抗体

ABIN2774788 产品详细信息, 供应商: Log in to see
抗原
  • fbxo11
  • im:6906507
  • wu:fj83f06
  • zgc:153171
  • MGC84634
  • FBXO11
  • Fbxo11
  • DKFZp459P2410
  • FBX11
  • PRMT9
  • UBR6
  • VIT1
  • C80048
  • Jf
  • Vit1
  • F-box protein 11
  • F-box protein 11a
  • F-box only protein 11
  • FBXO11
  • fbxo11a
  • fbxo11
  • CpipJ_CPIJ009919
  • CpipJ_CPIJ017549
  • Bm1_52225
  • LOAG_02072
  • Fbxo11
  • LOC100351392
Alternatives
anti-人 F-Box Protein 11 抗体 for Immunofluorescence (fixed cells)
抗原表位
Middle Region
12
10
8
5
5
4
4
4
3
3
3
3
3
1
1
1
适用
犬, 豚鼠, 马, 人, 小鼠, 兔, 大鼠, 斑马鱼
80
27
26
4
4
4
3
3
3
3
3
2
2
1
1
1
宿主

59
21
克隆类型
多克隆
标记
非结合性
3
3
3
2
2
2
1
1
1
1
1
1
1
1
1
1
1
应用范围
Chromatin Immunoprecipitation (ChIP), Western Blotting (WB)
62
32
16
13
12
10
6
4
2
1
1
1
1
1
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免疫原 The immunogen is a synthetic peptide directed towards the middle region of human FBXO11
Blocking Peptide Blocking peptide for this product available: ABIN976727
序列 HDVEFIRHDR FFCDCGAGTL SNPCTLAGEP THDTDTLYDS APPIESNTLQ
预测反应 Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
产品特性 This is a rabbit polyclonal antibody against FBXO11. It was validated on Western Blot using a cell lysate as a positive control.
纯化方法 Affinity Purified
别名 FBXO11 (FBXO11 Antibody 摘要)
背景 FBXO11 is a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. Alternatively spliced transcript variants encoding distinct isoforms have been identified for FBXO11.This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene.
Alias Symbols: FBX11, FLJ12673, MGC44383, PRMT9, UG063H01, VIT1, UBR6
Protein Interaction Partner: SKP1, ERN1, DTL, CUL1, EED, UBC, NEDD8, COPS5, COPS6, ELAVL1, USP16, HDAC6, BCL6, RBX1, TP53,
Protein Size: 843
分子量 94 kDa
基因ID 80204
NCBI登录号 NM_025133, NP_079409
UniProt Q6DF73
研究领域 Proteolysis / Ubiquitin
途径 Sensory Perception of Sound
应用备注 Optimal working dilutions should be determined experimentally by the investigator.
说明

Antigen size: 843 AA

限制 仅限研究用
状态 Liquid
浓度 Lot specific
缓冲液 Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
储存液 Sodium azide
注意事项 This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
注意事项 Avoid repeated freeze-thaw cycles.
储存条件 -20 °C
储存方法 For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
厂商提供的图像
Western Blotting (WB) image for anti-F-Box Protein 11 (FBXO11) (Middle Region) 抗体 (ABIN2774788) WB Suggested Anti-FBXO11 Antibody Titration: 0.2-1 ug/ml
ELISA Titer:
Chromatin Immunoprecipitation (ChIP) image for anti-F-Box Protein 11 (FBXO11) (Middle Region) 抗体 (ABIN2774788) Quiescent human colon carcinoma HCT116 cultures were treated with 10 % FBS for three ...
背景 Lee, Pal, Tasaki, Roy, Jiang, An, Banerjee, Kwon: "Synthetic heterovalent inhibitors targeting recognition E3 components of the N-end rule pathway." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 105, Issue 1, pp. 100-5, 2008 (PubMed).