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SRF 抗体 (N-Term)

SRF 适用: 人, 小鼠, 大鼠, 犬, Pig, Cow, 兔, 斑马鱼 WB, ChIP 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2774664
发货至: 中国
  • 抗原 See all SRF 抗体
    SRF (Serum Response Factor (SRF))
    抗原表位
    • 19
    • 18
    • 15
    • 10
    • 6
    • 4
    • 2
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    • 2
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    • 2
    • 1
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    N-Term
    适用
    • 86
    • 79
    • 44
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠, 犬, Pig, Cow, 兔, 斑马鱼
    宿主
    • 94
    • 8
    • 1
    • 1
    克隆类型
    • 94
    • 10
    多克隆
    标记
    • 51
    • 5
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    • 4
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    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    This SRF antibody is un-conjugated
    应用范围
    • 89
    • 39
    • 39
    • 26
    • 24
    • 16
    • 8
    • 8
    • 6
    • 4
    • 2
    • 2
    • 2
    • 1
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    Western Blotting (WB), Chromatin Immunoprecipitation (ChIP)
    序列
    ATGGYGPVSG AVSGAKPGKK TRGRVKIKME FIDNKLRRYT TFSKRKTGIM
    交叉反应
    牛, 犬, 小鸡, 人, 小鼠, 大鼠
    预测反应
    Cow: 100%, Dog: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
    产品特性
    This is a rabbit polyclonal antibody against SRF. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Protein A purified
    免疫原
    The immunogen is a synthetic peptide directed towards the N terminal region of human SRF
    Top Product
    Discover our top product SRF Primary Antibody
  • 应用备注
    WB Suggested Anti-SRF Antibody Titration: 1.25 µg/mL
    ELISA Titer: 1:1562500
    Positive Control: Jurkat cell lysate.
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 508 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    SRF (Serum Response Factor (SRF))
    Abstract
    SRF 产品
    别名
    AW049942 antibody, AW240594 antibody, MCM1 antibody, SRFX antibody, XSRF antibody, srf-A antibody, RGD1559787 antibody, srf antibody, srf1 antibody, serum response factor antibody, serum response factor L homeolog antibody, serum response factor a antibody, Srf antibody, SRF antibody, srf.L antibody, srfa antibody
    背景
    SRF is a ubiquitous nuclear protein that stimulates both cell proliferation and differentiation. It is a member of the MADS (MCM1, Agamous, Deficiens, and SRF) box superfamily of transcription factors. This protein binds to the serum response element (SRE) in the promoter region of target genes. This protein regulates the activity of many immediate-early genes, for example c-fos, and thereby participates in cell cycle regulation, apoptosis, cell growth, and cell differentiation. This gene is the downstream target of many pathways, for example, the mitogen-activated protein kinase pathway (MAPK) that acts through the ternary complex factors (TCFs).
    Alias Symbols: MCM1
    Protein Interaction Partner: Camk2d, ZIC3, ELK1, SRFBP1, SRF, NFKB1, PRKDC, CIRBP, ALDH3A1, SUMO1, UBE2I, SHBG, TRIM63, KDM6A, MYOCD, MKL1, CNTN2, CSNK2A1, SMARCA4, PELP1, KAT5, HDAC4, EPC1, SMAD7, HDAC3, MKL2, ATF6, BARX2, MAPKAPK2, FHL3, GATA4, CAMK2A, HOPX, PYCARD, NKX2-3, MINPP1,
    Protein Size: 508
    分子量
    52 kDa
    基因ID
    6722
    NCBI登录号
    NM_003131, NP_003122
    UniProt
    P11831
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