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Caspase 3 抗体 (N-Term)

Name: Caspase 3 抗体 (N-Term)
SKU: ABIN2774596
Availability: OutOfStock

CASP3 适用: 人, 大鼠, Cow, 犬, Pig, 兔, 豚鼠, 马 WB, IHC 宿主: 兔 Polyclonal unconjugated

WB Suggested Anti-CASP3 Antibody Titration: 5ug/ml Positive Control: Human Liver

Image no. 2 for anti-Caspase 3 (CASP3) (N-Term) antibody (ABIN2774596)

Immunofluorescent Caspase 3 detection in HeLa cells after induction of apoptosis (red fluorescence).

IHC

3 images

(2 references)

产品编号 ABIN2774596

发货至: 中国

Datasheet as PDF

抗原 See all Caspase 3 (CASP3) 抗体

Caspase 3 (CASP3)
抗原表位
19

16

16

16

16

16

16

15

13

13

12

11

10

9

8

7

7

6

6

6

5

5

4

4

3

3

3

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
N-Term
适用
278

193

148

30

17

9

9

9

6

6

5

5

4

3

2

2

1

1

1
人, 大鼠, Cow, 犬, Pig, 兔, 豚鼠, 马
宿主
279

40

4

2

2
兔
Compatible Secondaries
克隆类型
273

53
多克隆
标记
158

26

21

14

11

11

9

9

9

9

9

6

6

6

6

6

6

2

2

1
This Caspase 3 antibody is un-conjugated
应用范围
251

108

103

85

79

65

52

36

31

29

28

19

10

6

3

2

1

1

1

1
Western Blotting (WB), Immunohistochemistry (IHC)

序列

MENTENSVDS KSIKNLEPKI IHGSESMDSG ISLDNSYKMD YPEMGLCIII

预测反应

Cow: 84%, Dog: 84%, Guinea Pig: 84%, Horse: 92%, Human: 100%, Pig: 92%, Rabbit: 84%, Rat: 84%

产品特性

This is a rabbit polyclonal antibody against CASP3. It was validated on Western Blot using a cell lysate as a positive control.

纯化方法

Protein A purified

免疫原

The immunogen is a synthetic peptide directed towards the N terminal region of human CASP3

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anti-Caspase 3 (CASP3) (AA 60-100) antibody
CASP3 适用: 人, 小鼠, 大鼠, Cow, 山羊 WB, IF (cc) 宿主: 兔 Polyclonal unconjugated

anti-Caspase 3 (CASP3) (AA 67-175) antibody
CASP3 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Caspase 3 (CASP3) (AA 55-160) antibody
CASP3 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Caspase 3 (CASP3) (AA 220-236), (C-Term) antibody
CASP3 适用: 人 WB, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated

anti-Caspase 3 (CASP3) (AA 11-120) antibody
CASP3 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), FACS, IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Caspase 3 (CASP3) antibody
CASP3 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 小鼠 Monoclonal 5E1 unconjugated

anti-Caspase 3 (CASP3) (cleaved) antibody
CASP3 适用: 人, 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Caspase 3 (CASP3) (Internal Region) antibody
CASP3 适用: 人, 小鼠, 大鼠, Cow WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Caspase 3 (CASP3) (pSer150) antibody
CASP3 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Caspase 3 (CASP3) (AA 100-200) antibody
CASP3 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

应用备注

Optimal working dilutions should be determined experimentally by the investigator.

说明

Antigen size: 277 AA

限制

仅限研究用
状态

Liquid

浓度

Lot specific

缓冲液

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freeze-thaw cycles.

储存条件

-20 °C

储存方法

For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Korkmaz-Icöz, Sistori, Loganathan, Sayour, Brlecic, Radovits, Brune, Karck, Szabó: "Bone Marrow Culture-Derived Conditioned Medium Recovers Endothelial Function of Vascular Grafts following In Vitro Ischemia/Reperfusion Injury in Diabetic Rats." in: Stem cells international, Vol. 2022, pp. 7019088, (2022) (PubMed).

Jeong, Lee, Shim, Hur: "A scaffold-free surface culture of B16F10 murine melanoma cells based on magnetic levitation." in: Cytotechnology, Vol. 68, Issue 6, pp. 2323-2334, (2016) (PubMed).
抗原

Caspase 3 (CASP3)

别名

CASP3 (CASP3 产品)

别名

CPP32 antibody, CPP32B antibody, SCA-1 antibody, A830040C14Rik antibody, AC-3 antibody, Apopain antibody, CC3 antibody, Caspase-3 antibody, Lice antibody, Yama antibody, mldy antibody, xcpp32 antibody, casp3 antibody, zgc:100890 antibody, CASP-3 antibody, caspase-3 antibody, caspase 3 antibody, caspase 3 S homeolog antibody, caspase 3, apoptosis-related cysteine peptidase a antibody, caspase 3, apoptosis-related cysteine peptidase antibody, CASP3 antibody, Casp3 antibody, casp3.S antibody, casp3a antibody

背景

CASP3 is a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 6, 7 and 9, and the protein itself is processed by caspases 8, 9 and 10. It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein, which is associated with neuronal death in Alzheimer's disease. Alternative splicing of this gene results in two transcript variants that encode the same protein.
Alias Symbols: CPP32, SCA-1, CPP32B
Protein Interaction Partner: BAX, PARP1, PTGES3, XIAP, CRYAB, BIRC7, UBC, MDM2, Gzmb, VIM, STAT1, SPTAN1, ROCK1, GSN, DFFA, CASP9, CASP7, CASP6, CASP2, BID, ARHGDIA, TNFSF10, PLA2G4B, CDKN1A, RB1, PRKDC, GLRX, GATA1, SOCS5, YWHAG, MAPK9, MAPK8, SP1, PKN1, CASP8, BIRC3, BIRC2, ZBTB16,
Protein Size: 277

分子量

32 kDa

基因ID

836

NCBI登录号

NM_004346, NP_004337

UniProt

P42574

途径

Apoptosis, Caspase Cascade in Apoptosis, Sensory Perception of Sound, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Activated T Cell Proliferation