Macrophage Mannose Receptor 1 抗体 (PE)
(5 references)-
- 抗原 See all Macrophage Mannose Receptor 1 (MRC1) 抗体
- Macrophage Mannose Receptor 1 (MRC1) (Mannose Receptor, C Type 1 (MRC1))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This Macrophage Mannose Receptor 1 antibody is conjugated to PE
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应用范围
- Flow Cytometry (FACS)
- 特异性
- The mouse monoclonal antibody 15-2 (also known as MR15-2) recognizes an extracellular epitope of CD206 (macrophage mannose receptor, MMR), a 162-175 kDa type I transmembrane protein expressed mainly on macrophages, dendritic cells and hepatic or lymphatic endothelial cells, but not on monocytes.
- 交叉反应 （详细）
- Human
- 纯化方法
- Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
- 免疫原
- Purified human mannose receptor
- 克隆位点
- 15-2
- 亚型
- IgG1 kappa
- Top Product
- Discover our top product MRC1 Primary Antibody
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anti-Mannose Receptor, C Type 1 (MRC1) (AA 22-130) antibody
MRC1 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 5C11 unconjugated
anti-Mannose Receptor, C Type 1 (MRC1) antibodyMRC1 适用: 人 FACS, WB, IP, ICC, IHC (fro) 宿主: 小鼠 Monoclonal 15-2 unconjugated
anti-Mannose Receptor, C Type 1 (MRC1) antibodyMRC1 适用: 人 FACS, WB, IP, ICC, IHC (fro), Func 宿主: 小鼠 Monoclonal 15-2 unconjugated
anti-Mannose Receptor, C Type 1 (MRC1) (AA 201-300) antibodyMRC1 适用: 人, 小鼠, 大鼠, 犬 FACS, WB, ELISA, IHC (p), IF (p) 宿主: 兔 Polyclonal unconjugated
anti-Mannose Receptor, C Type 1 (MRC1) (Internal Region) antibodyMRC1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Mannose Receptor, C Type 1 (MRC1) antibody (FITC)MRC1 适用: 人 FACS 宿主: 小鼠 Monoclonal 15-2 FITC
anti-Mannose Receptor, C Type 1 (MRC1) antibody (APC)MRC1 适用: 人 FACS 宿主: 小鼠 Monoclonal 15-2 APC
anti-Mannose Receptor, C Type 1 (MRC1) (AA 225-492) antibodyMRC1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Mannose Receptor, C Type 1 (MRC1) antibodyMRC1 适用: 人 WB, IHC (p) 宿主: 小鼠 Monoclonal CL0387 unconjugated
anti-Mannose Receptor, C Type 1 (MRC1) (AA 359-388) antibodyMRC1 适用: 人, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μL reagent / 100 μL of whole blood or 106 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.
- 说明
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The purified antibody is conjugated with R-Phycoerythrin (PE) under optimum conditions. The conjugate is purified by size-exclusion chromatography and adjusted for direct use. No reconstitution is necessary.
- 限制
- 仅限研究用
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- 缓冲液
- Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 储存方法
- Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
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: "An unrestrained proinflammatory M1 macrophage population induced by iron impairs wound healing in humans and mice." in: The Journal of clinical investigation, Vol. 121, Issue 3, pp. 985-97, (2011) (PubMed).
: "HIV-1 gp120 mannoses induce immunosuppressive responses from dendritic cells." in: PLoS pathogens, Vol. 3, Issue 11, pp. e169, (2007) (PubMed).
: "Mannose receptor regulation of macrophage cell migration." in: Journal of leukocyte biology, Vol. 82, Issue 3, pp. 585-93, (2007) (PubMed).
: "Fine discrimination in the recognition of individual species of phosphatidyl-myo-inositol mannosides from Mycobacterium tuberculosis by C-type lectin pattern recognition receptors." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 177, Issue 3, pp. 1805-16, (2006) (PubMed).
: "Modulation of macrophage differentiation and activation by decoy receptor 3." in: Journal of leukocyte biology, Vol. 75, Issue 3, pp. 486-94, (2004) (PubMed).
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: "An unrestrained proinflammatory M1 macrophage population induced by iron impairs wound healing in humans and mice." in: The Journal of clinical investigation, Vol. 121, Issue 3, pp. 985-97, (2011) (PubMed).
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- 抗原
- Macrophage Mannose Receptor 1 (MRC1) (Mannose Receptor, C Type 1 (MRC1))
- 别名
- CD206 (MRC1 产品)
- 别名
- CD206 antibody, CLEC13D antibody, CLEC13DL antibody, MMR antibody, MRC1L1 antibody, bA541I19.1 antibody, AW259686 antibody, MR antibody, mrc1 antibody, MGC86525 antibody, MRC1 antibody, MRC1L-A antibody, mannose receptor C-type 1 antibody, mannose receptor, C type 1 antibody, mannose receptor C-type 1 L homeolog antibody, mediator of replication checkpoint 1 antibody, MRC1 antibody, Mrc1 antibody, mrc1.L antibody, mrc1 antibody
- 背景
- Mannose receptor C-type 1,CD206 (macrophage mannose receptor, MMR), also known as mannose receptor C1 (MRC1), is a type I transmembrane glycoprotein serving as pattern recognition receptor for carbogydrate groups on the surface of bacteria, fungi and other pathogens. Expressed mainly on tissue macrophages and dendritic cells, CD206 mediates endocytosis of these pathogens and presentation of their antigens to the adaptive immune system. CD206 can also be detected in a soluble form in human plasma and is elevated in patients with acute sepsis.,MMR, MRC1, CLEC13DL
- 基因ID
- 4360
- UniProt
- P22897
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