(6 references)-
- 抗原 See all CD94 (KLRD1) 抗体
- CD94 (KLRD1) (Killer Cell Lectin-Like Receptor Subfamily D, Member 1 (KLRD1))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This CD94 antibody is conjugated to FITC
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应用范围
- Flow Cytometry (FACS)
- 特异性
- The mouse monoclonal antibody HP-3D9 recognizes an extracellular epitope of CD94, a 70 kDa type II transmembrane glycoprotein expressed on NK cells, NK-T cells, and subsets of CD8+ T cells and gamma/delta T cells.
- 交叉反应 （详细）
- Human
- 纯化方法
- Purified antibody is conjugated with fluorescein isothiocyanate (FITC) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
- 免疫原
- Cultured human NK cells
- 克隆位点
- HP-3D9
- 亚型
- IgG1 kappa
- Top Product
- Discover our top product KLRD1 Primary Antibody
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anti-Killer Cell Lectin-Like Receptor Subfamily D, Member 1 (KLRD1) (AA 32-179) antibody
KLRD1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Killer Cell Lectin-Like Receptor Subfamily D, Member 1 (KLRD1) antibodyKLRD1 适用: 人 WB, FACS, ELISA 宿主: 小鼠 Monoclonal 1H1 unconjugated
anti-Killer Cell Lectin-Like Receptor Subfamily D, Member 1 (KLRD1) (AA 32-179) antibodyKLRD1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Killer Cell Lectin-Like Receptor Subfamily D, Member 1 (KLRD1) (AA 42-168) antibodyKLRD1 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Killer Cell Lectin-Like Receptor Subfamily D, Member 1 (KLRD1) antibody (PE)KLRD1 适用: 人 FACS 宿主: 小鼠 Monoclonal HP-3D9 PE
anti-Killer Cell Lectin-Like Receptor Subfamily D, Member 1 (KLRD1) (C-Term) antibodyKLRD1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Killer Cell Lectin-Like Receptor Subfamily D, Member 1 (KLRD1) antibodyKLRD1 适用: 人 FACS 宿主: 小鼠 Monoclonal HP-3D9 unconjugated
anti-Killer Cell Lectin-Like Receptor Subfamily D, Member 1 (KLRD1) antibody (APC)KLRD1 适用: 人 FACS 宿主: 小鼠 Monoclonal HP-3D9 APC
anti-Killer Cell Lectin-Like Receptor Subfamily D, Member 1 (KLRD1) antibodyKLRD1 适用: 人 FACS, IHC 宿主: 小鼠 Monoclonal B-D49 unconjugated
anti-Killer Cell Lectin-Like Receptor Subfamily D, Member 1 (KLRD1) (AA 31-57), (N-Term) antibodyKLRD1 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB21999 unconjugated
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- 应用备注
- Flow cytometry: The reagent is designed for analysis of human blood cells using 4 μL reagent / 100 μL of whole blood or 106 cells in a suspension. The content of a vial (0.4 ml) is sufficient for 100 tests.
- 说明
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The purified antibody is conjugated with Fluorescein isothiocyanate (FITC) under optimum conditions. The reagent is free of unconjugated FITC and adjusted for direct use. No reconstitution is necessary.
- 限制
- 仅限研究用
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- 缓冲液
- Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 储存方法
- Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
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: "CD94 surface density identifies a functional intermediary between the CD56bright and CD56dim human NK-cell subsets." in: Blood, Vol. 115, Issue 2, pp. 274-81, (2010) (PubMed).
: "Modulation of the tumor cell phenotype by IFN-gamma results in resistance of uveal melanoma cells to granule-mediated lysis by cytotoxic lymphocytes." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 180, Issue 6, pp. 3766-74, (2008) (PubMed).
: "The role of lesional T cells in recalcitrant psoriasis during infliximab therapy." in: European journal of dermatology : EJD, Vol. 15, Issue 6, pp. 454-8, (2005) (PubMed).
: "The inhibitory NK cell receptor CD94/NKG2A and the activating receptor CD94/NKG2C bind the top of HLA-E through mostly shared but partly distinct sets of HLA-E residues." in: European journal of immunology, Vol. 34, Issue 1, pp. 81-90, (2004) (PubMed).
: "Disordered expression of inhibitory receptors on the NK1-type natural killer (NK) leukaemic cells from patients with hypersensitivity to mosquito bites." in: Clinical and experimental immunology, Vol. 120, Issue 3, pp. 413-9, (2000) (PubMed).
: "CD94 and a novel associated protein (94AP) form a NK cell receptor involved in the recognition of HLA-A, HLA-B, and HLA-C allotypes." in: Immunity, Vol. 5, Issue 2, pp. 163-72, (1996) (PubMed).
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: "CD94 surface density identifies a functional intermediary between the CD56bright and CD56dim human NK-cell subsets." in: Blood, Vol. 115, Issue 2, pp. 274-81, (2010) (PubMed).
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- 抗原
- CD94 (KLRD1) (Killer Cell Lectin-Like Receptor Subfamily D, Member 1 (KLRD1))
- 别名
- CD94 (KLRD1 产品)
- 别名
- CD94 antibody, CD94-B antibody, Cd94 antibody, killer cell lectin like receptor D1 antibody, killer cell lectin-like receptor subfamily D, member 1 antibody, killer cell lectin-like receptor, subfamily D, member 1 antibody, KLRD1 antibody, Klrd1 antibody
- 背景
- Killer cell lectin like receptor D1,CD94, also known as KLRD1 (killer cell lectin-like receptor D1), is a transmembrane glycoprotein of the C-type lectin family, which forms disulfide-linked heterodimers with NKG2A, B, C, E, H proteins, constituting functionally distinct receptors of NK cells and related cell types. CD94/NKG2A and CD94/NKG2B heterodimers serve as inhibitory, whereas CD94/NKG2C and CD94/NKG2E as activating receptors. The ligand for CD94/NKG2 complexes has been identified as HLA-E. Extent of CD94 expression on NK cell surface can be used to demonstrate their progress through the differentiation process.,KLR-D1, KLRD1, KCLLRD1
- 基因ID
- 3824
- UniProt
- Q13241
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