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Insulin 抗体

INS 适用: 人, Pig, Cow WB, IHC (p), EIA 宿主: 小鼠 Monoclonal E2E3 unconjugated
产品编号 ABIN272321
发货至: 中国
  • 抗原 See all Insulin (INS) 抗体
    Insulin (INS)
    适用
    • 189
    • 106
    • 91
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    人, Pig, Cow
    宿主
    • 137
    • 85
    • 13
    • 2
    • 1
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    小鼠
    克隆类型
    • 143
    • 98
    单克隆
    标记
    • 120
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    This Insulin antibody is un-conjugated
    应用范围
    • 82
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    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    特异性
    This antibody detects Insulin.
    纯化方法
    Purified
    免疫原
    Hybridoma produced by the fusion of splenocytes from mice immunized with full-length insulin protein and mouse myeloma cells.
    克隆位点
    E2E3
    亚型
    IgG1
    Top Product
    Discover our top product INS Primary Antibody
  • 应用备注
    ELISA. Immunohistochemistry on formalin-fixed, paraffin-embedded tissues (1-2 μg/mL, incubateat room temp. for at least 1 hr. ). Western blot (1-5 μg/mL).
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 缓冲液
    Phosphate buffered saline with 0.08 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    -20 °C
    储存方法
    Store the lyophilized antibody at -20 °C. Following reconstitution it is stable for two weeks at 2 - 8 °C. Frozen aliquots are stable for 6 months when stored at -20 °C.
    有效期
    6 months
  • 抗原
    Insulin (INS)
    别名
    Insulin (INS 产品)
    别名
    IDDM2 antibody, ILPR antibody, IRDN antibody, MODY10 antibody, ins1 antibody, xins antibody, ins1-a antibody, Insulin antibody, AA986540 antibody, Ins-2 antibody, InsII antibody, Mody antibody, Mody4 antibody, proinsulin antibody, zgc:109842 antibody, igf2-A antibody, ins antibody, ins-a antibody, ins-b antibody, insulin antibody, insulin precursor antibody, insulin II antibody, preproinsulin antibody, insulin L homeolog antibody, insulin S homeolog antibody, INS antibody, INS-IGF2 antibody, ins antibody, Ins antibody, PIN antibody, Ins2 antibody, ins.L antibody, ins.S antibody
    背景
    Insulin is one of the major regulatory hormones of intermediate metabolism throughout the body. The biological actions of this hormone involve integration of carbohydrate, protein, and lipid metabolism. Insulin enhances membrane transport of glucose, amino acids, and certain ions. It also promotes glycogen storage, formation of triglycerides and synthesis of proteins and nucleic acids. Immunocytochemical investigations have localized insulin in the B cells of pancreatic islets of Langerhans. Deficiency of insulin results in diabetes mellitus, one of the leading causes of morbidity and mortality in the general population. Insulin is also present in tumors of B cell origin such as insulinoma.Synonyms: INS
    基因ID
    3630
    NCBI登录号
    NP_000198
    UniProt
    P01308
    途径
    NF-kappaB Signaling, RTK signaling, Positive Regulation of Peptide Hormone Secretion, Peptide Hormone Metabolism, Hormone Activity, Carbohydrate Homeostasis, ER-Nucleus Signaling, Regulation of Carbohydrate Metabolic Process, Feeding Behaviour, Autophagy, Negative Regulation of intrinsic apoptotic Signaling, Brown Fat Cell Differentiation, Positive Regulation of fat Cell Differentiation
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