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CD83 抗体

CD83 适用: 人 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN272283
发货至: 中国
  • 抗原 See all CD83 抗体
    CD83
    适用
    • 66
    • 43
    • 19
    • 4
    • 2
    • 1
    宿主
    • 55
    • 20
    • 10
    • 1
    克隆类型
    • 57
    • 26
    • 1
    多克隆
    标记
    • 35
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    • 2
    • 2
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    This CD83 antibody is un-conjugated
    应用范围
    • 57
    • 43
    • 19
    • 13
    • 9
    • 4
    • 3
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    特异性
    This antibody detects endogenous levels of CD83 protein. (region surrounding Pro130)
    交叉反应 (详细)
    Species reactivity (expected):Mouse and Rat.
    Species reactivity (tested):Human.
    纯化方法
    Affinity Chromatography using epitope-specific immunogen
    Top Product
    Discover our top product CD83 Primary Antibody
  • 应用备注
    ELISA: 1/1000approx. 1/5000. Western Blot: 1/500approx. 1/1000. Immunohistochemistry: 1/50approx. 1/200.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    Phosphate buffered saline (PBS), pH ~7.2, 0.05 % Sodium Azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store undiluted at 2-8 °C one month or (in aliquots) at -20 °C for longer.
  • 抗原
    CD83
    别名
    CD83 (CD83 产品)
    别名
    BL11 antibody, HB15 antibody, CD83 molecule antibody, CD83 antigen antibody, Cd83 antibody, CD83 antibody
    背景
    CD83 is a heavily glycosylated membrane protein of the immunoglobulin (Ig) superfamily that is expressed in mature dendritic cells, Langerhans cells and interdigitating reticulum cells within lymphoid tissues. Structurally, CD83 resembles other Ig superfamily members, which have an extracellular V-type Ig-like domain, a single transmembrane domain and a 40 residue cytoplasmic tail. CD83 expression is used as a marker for mature, antigen presenting dendritic cells that are capable of generating tumor-specific T cell immunity, a phenotype with implications as an anticancer vaccine. CD83-IgG1(fc) chimera studies indicate that CD83 is a sialic acid-binding, Ig-like lectin (Siglec) adhesion molecule that is involved in cell adhesion/signaling by hosting dendritic cell interactions with monocytes and CD8+ T cells.Synonyms: B-cell activation protein, Cell surface protein HB15, HB15
    分子量
    approx. 23, 45 kDa
    基因ID
    9308
    NCBI登录号
    NP_001035370
    UniProt
    Q01151
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