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MLX 抗体

MLX 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN272258
发货至: 中国
  • 抗原 See all MLX 抗体
    MLX (MAX-Like Protein X (MLX))
    适用
    • 58
    • 22
    • 22
    • 11
    • 9
    • 9
    • 8
    • 8
    • 8
    • 5
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    人, 小鼠, 大鼠
    宿主
    • 50
    • 5
    • 3
    克隆类型
    • 55
    • 3
    多克隆
    标记
    • 28
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This MLX antibody is un-conjugated
    应用范围
    • 43
    • 21
    • 13
    • 13
    • 9
    • 7
    • 6
    • 3
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    特异性
    This antibody detects endogenous levels of Mlx protein. (region surrounding Gln136)
    交叉反应 (详细)
    Species reactivity (expected):Mouse and Rat.
    Species reactivity (tested):Human.
    纯化方法
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
    纯度
    > 95 % pure by SDS-PAGE
    Top Product
    Discover our top product MLX Primary Antibody
  • 应用备注
    ELISA: 1: 10000approx. 1: 20000. WB: 1: 500approx. 1: 1000.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1,0 mg/mL
    缓冲液
    Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    DO NOT FREEZE!
    储存条件
    4 °C
    储存方法
    Store the antibody undiluted at 2-8 °C.
  • 抗原
    MLX (MAX-Like Protein X (MLX))
    别名
    Max-Like Protein X (MLX 产品)
    别名
    MAD7 antibody, MXD7 antibody, TCFL4 antibody, bHLHd13 antibody, Tcfl4 antibody, im:7146242 antibody, wu:fb61a01 antibody, wu:fb99c01 antibody, zgc:112409 antibody, DKFZp468J1719 antibody, MLX, MAX dimerization protein antibody, MAX-like protein X antibody, max-like protein X antibody, MLX antibody, Mlx antibody, mlx antibody, LOC786043 antibody
    背景
    Max is a nuclear localized bHLH-Zip protein that forms homodimers or heterodimers with Myc family members, including Myc, Mad 1, Mad 3, Mad 4, Mxi1 and Mnt (or Rox). These dimers bind to the E-box sequence CACGTG in order to regulate cell growth, proliferation and apoptosis. Mlx (Max-like protein X) is a bHLH-Zip protein that is structurally and functionally related to Max. Like Max, Mlx is broadly expressed in many tissues and has a long half-life. Mlx also forms homodimers or heterodimers with members of the Myc family, specifically Mad 1, Mad 4 and Rox, and members of the Mondo family, to repress or activate transcription from CACGTG E-boxes. MondoA forms weak homodimers and preferentially forms heterodimers with Mlx. The MondoA/Mlx complex is primarily localized to the cytoplasm, but will translocate to the nucleus in response to leptomycin B. Mlx can also dimerize with WBSCR14, a protein involved in Williams-Beuren syndrome (WBS), to repress E-box transcription, which provides further evidence that Mlx is a critical element in a transcription factor network.Synonyms: BigMax protein, MLX, Max-like bHLHZip protein, TCFL4, Transcription factor-like protein 4
    分子量
    approx. 33 kDa
    基因ID
    6945
    NCBI登录号
    NP_733752
    UniProt
    Q9UH92
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