电话:
400-7060-959
传真:
+86 10 56315212-8813
电子邮件:
orders@antibodies-online.cn

FXR2 抗体

FXR2 适用: 人, 小鼠 WB, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN272201
发货至: 中国
  • 抗原 See all FXR2 抗体
    FXR2 (Fragile X Mental Retardation, Autosomal Homolog 2 (FXR2))
    适用
    • 33
    • 21
    • 5
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    人, 小鼠
    宿主
    • 27
    • 6
    克隆类型
    • 29
    • 4
    多克隆
    标记
    • 26
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This FXR2 antibody is un-conjugated
    应用范围
    • 25
    • 12
    • 7
    • 7
    • 5
    • 3
    • 3
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    特异性
    This antibody detects endogenous levels of FXR2 protein. (region surrounding Glu576)
    交叉反应 (详细)
    Species reactivity (tested):Human, Mouse.
    纯化方法
    Affinity-Chromatography using epitope-specific immunogen
    Top Product
    Discover our top product FXR2 Primary Antibody
  • 应用备注
    ELISA: 1: 10000approx. 1: 20000. WB: 1: 500approx. 1: 1000. IHC: 1: 50approx. 1: 200.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    Phosphate buffered saline (PBS), pH ~7.2, 15 mM Sodium Azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    FXR2 (Fragile X Mental Retardation, Autosomal Homolog 2 (FXR2))
    别名
    FXR2 (FXR2 产品)
    别名
    id:ibd5046 antibody, zgc:56215 antibody, zgc:77472 antibody, FMR1L2 antibody, FXR2P antibody, Fxr2h antibody, FMR1 autosomal homolog 2 antibody, fragile X mental retardation, autosomal homolog 2 antibody, FXR2 antibody, fxr2 antibody, Fxr2 antibody
    背景
    Fragile X syndrome is the most frequent form of inherited mental retardation and is the result of transcriptional silencing of the FMR1 gene on the X chromosome. The FMR1 gene contains a distinct CpG dinucleotide repeat located in the 5' untranslated region of the gene, and in the fragile X syndrome this tandem repeat is substantially amplified and subjected to extensive methylation and enhanced transcriptional silencing. The FMR1 protein (or FMRP) is an RNA-binding protein that associates with polyribosomes and is a likely component of a messenger ribonuclear protein (mRNP) particle. It contains several features that are characteristics of RNA-binding proteins, including two hnRNPK homology (KH) domains and an RGG amino acid motif (RGG box). FMR1 can also interact with two fragile X syndrome related factors, FXR1 and FXR2, and these proteins form heterodimers through their N-terminal coilcoiled domains. FMR1 localizes to both the nucleus and the cytoplasm, and since it contains both a nuclear localization signal and a nuclear export signal it is also implicated in the nucleo-cytoplasmic transport of mRNAs.Synonyms: FMR1L2, Fragile X mental retardation syndrome-related protein 2
    分子量
    approx. 65 kDa
    基因ID
    9513
    NCBI登录号
    NP_004851
    UniProt
    P51116
You are here:
客服