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BMX 抗体

BMX 适用: 人, 小鼠 WB, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN272021
发货至: 中国
  • 抗原 See all BMX 抗体
    BMX (BMX Non-Receptor Tyrosine Kinase (BMX))
    适用
    • 59
    • 50
    • 21
    • 5
    • 1
    • 1
    • 1
    人, 小鼠
    宿主
    • 73
    • 2
    克隆类型
    • 73
    • 2
    多克隆
    标记
    • 42
    • 3
    • 3
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    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    This BMX antibody is un-conjugated
    应用范围
    • 72
    • 37
    • 34
    • 26
    • 26
    • 21
    • 16
    • 7
    • 5
    • 4
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    特异性
    This antibody detects endogenous levels of ETK protein. (region surrounding Lys35)
    交叉反应 (详细)
    Species reactivity (tested):Human, Mouse.
    纯化方法
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
    纯度
    > 95 % pure by SDS-PAGE
    Top Product
    Discover our top product BMX Primary Antibody
  • 应用备注
    ELISA: 1: 5000approx. 1: 10000. WB: 1: 500approx. 1: 1000. IHC: 1: 50approx. 1: 200.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1,0 mg/mL
    缓冲液
    Phosphate buffered saline (PBS), pH 7.2., 15 mM sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    DO NOT FREEZE!
    储存条件
    4 °C
    储存方法
    Store the antibody undiluted at 2-8 °C.
  • 抗原
    BMX (BMX Non-Receptor Tyrosine Kinase (BMX))
    别名
    BMX (BMX 产品)
    别名
    BMX antibody, ETK antibody, PSCTK2 antibody, PSCTK3 antibody, Etk antibody, Etk/Bmx antibody, Tyro8 antibody, RGD1565643 antibody, BMX non-receptor tyrosine kinase antibody, BMX antibody, bmx antibody, Bmx antibody
    背景
    Etk, also known as BMX, is a member of the Bruton's tyrosine kinase (Btk) family (1). It is expressed in a variety of hematopoietic, epithelial and endothelial cells. Etk, like other Btk family members, contains a pleckstrin homology (PH) domain and Src homology SH3 and SH2 domains. It participates in multiple signal transduction pathways (2). Phosphorylation of Tyr566 by Src kinase is required for activation of Etk in vivo (3). In endothelial and epithelial cells, Etk is regulated by FAK through phosphorylation at Tyr40 (4).Synonyms: Bone marrow tyrosine kinase gene in chromosome X protein, Cytoplasmic tyrosine-protein kinase BMX, ETK, Epithelial and endothelial tyrosine kinase, NTK38
    分子量
    approx. 78 kDa
    基因ID
    660
    NCBI登录号
    NP_001712
    UniProt
    P51813
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