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FCER2 抗体

FCER2 适用: 人 FACS, WB, IHC (fro) 宿主: 小鼠 Monoclonal M unconjugated
产品编号 ABIN2689105
发货至: 中国
  • 抗原 See all FCER2 抗体
    FCER2 (Fc Fragment of IgE, Low Affinity II, Receptor For (CD23) (FCER2))
    适用
    • 98
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    宿主
    • 57
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    小鼠
    克隆类型
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    单克隆
    标记
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    This FCER2 antibody is un-conjugated
    应用范围
    • 72
    • 52
    • 33
    • 20
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    • 10
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    • 2
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    Flow Cytometry (FACS), Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro))
    品牌
    BD Pharmingen™
    产品特性
    The M-L233 antibody reacts with the low affinity receptor for human IgE, FcεRII/CD23. CD23 is a type II membrane protein which can be expressed by B cells, monocytes, macrophages, eosinophils, platelets, and dendritic cells. CD23 can mediate IgE-dependent cytotoxicity and phagocytosis by macrophages and eosinophils. Soluble CD23 (sCD23) can be released by CD23+ cells as a result of proteolytic cleavage of membrane CD23. Larger fragments of sCD23 (e.g., 37-25 kDa) retain their IgE-binding capacity whereas smaller fragments (i.e., ≤ 12 kDa) do not. Soluble CD23 may have immunoregulatory effects on the growth and differentiation of B cells and other cell types. Profile of peripheral blood lymphocytes analyzed on a FACScan

    BD Pharmingen™ Purified Mouse Anti-Human CD23 - Purified - Clone M-L233 - Isotype Mouse IgG1, κ - Reactivity Hu - 0.5 mg
    纯化方法
    The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
    克隆位点
    M
    亚型
    IgG1 kappa
    Top Product
    Discover our top product FCER2 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    Aqueous buffered solution containing ≤0.09 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    Store undiluted at 4°C.
  • Saeland, Duvert, Moreau, Banchereau: "Human B cell precursors proliferate and express CD23 after CD40 ligation." in: The Journal of experimental medicine, Vol. 178, Issue 1, pp. 113-20, (1993) (PubMed).

    Delespesse, Hofstetter, Sarfati: "Low-affinity receptor for IgE (FcERII, CD23) and its soluble fragments." in: International archives of allergy and applied immunology, Vol. 90 Suppl 1, pp. 41-4, (1990) (PubMed).

    Gordon, Millsum, Flores-Romo, Gillis: "Regulation of resting and cycling human B lymphocytes via surface IgM and the accessory molecules interleukin-4, CD23 and CD40." in: Immunology, Vol. 68, Issue 4, pp. 526-31, (1990) (PubMed).

  • 抗原
    FCER2 (Fc Fragment of IgE, Low Affinity II, Receptor For (CD23) (FCER2))
    别名
    CD23 (FCER2 产品)
    别名
    BLAST-2 antibody, CD23 antibody, CD23A antibody, CLEC4J antibody, FCE2 antibody, IGEBF antibody, Fcer2a antibody, Fc fragment of IgE receptor II antibody, FCER2 antibody, Fcer2 antibody
    途径
    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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