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CD16 抗体 (Biotin)

CD16 适用: 猕猴, Cynomolgus, Baboon FACS 宿主: 小鼠 Monoclonal 3G8 Biotin
产品编号 ABIN2689004
发货至: 中国
  • 抗原 See all CD16 抗体
    CD16
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    猕猴, Cynomolgus, Baboon
    宿主
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    小鼠
    克隆类型
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    单克隆
    标记
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    This CD16 antibody is conjugated to Biotin
    应用范围
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    Flow Cytometry (FACS)
    品牌
    BD Pharmingen™
    产品特性
    Reacts with the 50-65 kDa transmembrane form of IgG Fc (FcγRIII), a human NK-cell-associated antigen. CD16 is expressed on NK cells as well as macrophages and granulocytes. Reports indicate that CD16 plays a role in signal transduction and NK cell activation. CD16 antibody blocks the binding of soluble immune complexes to granulocytes. This antibody is routinely tested by flow cytometric analysis. Other applications were tested during antibody development only or reported in the literature. Profile of peripheral blood lymphocytes analyzed on a FACScan

    BD Pharmingen™ Biotin Mouse Anti-Human CD16 - Biotin - Clone 3G8 - Isotype Mouse IgG1, κ - Reactivity Bab, Cyno, Rhe - 100 Tests
    纯化方法
    The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
    克隆位点
    3G8
    亚型
    IgG1 kappa
    Top Product
    Discover our top product CD16 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    样本量
    20 μL
    限制
    仅限研究用
  • 缓冲液
    Aqueous buffered solution containing BSA and ≤0.09 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    The antibody was conjugated with biotin under optimum conditions, and unreacted biotin was removed.
    储存条件
    4 °C
    储存方法
    Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
  • Wirthmueller, Kurosaki, Murakami, Ravetch: "Signal transduction by Fc gamma RIII (CD16) is mediated through the gamma chain." in: The Journal of experimental medicine, Vol. 175, Issue 5, pp. 1381-90, (1992) (PubMed).

    Stroncek, Skubitz, Plachta, Shankar, Clay, Herman, Fleit, McCullough: "Alloimmune neonatal neutropenia due to an antibody to the neutrophil Fc-gamma receptor III with maternal deficiency of CD16 antigen." in: Blood, Vol. 77, Issue 7, pp. 1572-80, (1991) (PubMed).

    Fleit, Wright, Unkeless: "Human neutrophil Fc gamma receptor distribution and structure." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 79, Issue 10, pp. 3275-9, (1982) (PubMed).

    Guesdon, Ternynck, Avrameas: "The use of avidin-biotin interaction in immunoenzymatic techniques." in: The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, Vol. 27, Issue 8, pp. 1131-9, (1979) (PubMed).

  • 抗原
    CD16
    别名
    CD16 (CD16 产品)
    别名
    Fcgr3 antibody, Fcgr3a antibody, CD16 antibody, FCGR3 antibody, FCGR3@ antibody, CD16b antibody, FCG3 antibody, FCR-10 antibody, FCRIII antibody, FCRIIIb antibody, FcRIII antibody, Fc fragment of IgG, low affinity IIa, receptor antibody, Fc fragment of IgG, low affinity IIIa, receptor (CD16a) antibody, Fc fragment of IgG receptor IIIb antibody, Fc fragment of IgG receptor IIIa antibody, Fc receptor, IgG, low affinity III antibody, Fc-gamma RIII antibody, Fcgr2a antibody, FCGR3A antibody, FCGR3B antibody, Fcgr3 antibody, FCGR3 antibody
    途径
    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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