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CD151 抗体

CD151 适用: 人 FACS, IP, IHC (fro) 宿主: 小鼠 Monoclonal 14A2-H1 unconjugated
产品编号 ABIN2688986
发货至: 中国
  • 抗原 See all CD151 抗体
    CD151
    适用
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    宿主
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    小鼠
    克隆类型
    • 52
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    单克隆
    标记
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    This CD151 antibody is un-conjugated
    应用范围
    • 42
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    Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro))
    品牌
    BD Pharmingen™
    产品特性
    Reacts with platelet-endothelial cell tetraspan antigen-3 (PETA-3), a 27 kD membrane glycoprotein, expressed on platelets, megakaryocytes, lymphocytes (weak), monocytes, endothelial cells and epithelial cells. PETA-3 (CD151) associates with β1 integrin in certain tissues. This has also been shown with other tetraspan superfamily members, like CD9, CD63 and α5β1. Reports indicate that this association or colocalization of CD151 with β1 integrin in tissues suggests a functional role of this molecule, however, this role has not been elucidated yet. It has also been reported that antibody 14A2.H1 is capable of platelet activation in vitro. Studies showed that different clones of CD151 monoclonal antibodies display strikingly different patterns of binding to human haemopoietic cells and tissue sections, and that this is due at least in part to the presence of the protein in complexes with different integrins. Profile of peripheral blood platelets analyzed by flow cytometry

    BD Pharmingen™ Purified Mouse Anti-Human CD151 - Purified - Clone 14A2.H1 - Isotype Mouse IgG1, κ - Reactivity Hu - 0.1 mg
    纯化方法
    The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
    克隆位点
    14A2-H1
    亚型
    IgG1 kappa
    Top Product
    Discover our top product CD151 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    Aqueous buffered solution containing ≤0.09 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    Store undiluted at 4°C.
  • Geary, Cambareri, Sincock, Fitter, Ashman: "Differential tissue expression of epitopes of the tetraspanin CD151 recognised by monoclonal antibodies." in: Tissue antigens, Vol. 58, Issue 3, pp. 141-53, (2001) (PubMed).

    Sincock, Mayrhofer, Ashman: "Localization of the transmembrane 4 superfamily (TM4SF) member PETA-3 (CD151) in normal human tissues: comparison with CD9, CD63, and alpha5beta1 integrin." in: The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, Vol. 45, Issue 4, pp. 515-25, (1997) (PubMed).

    Fitter, Tetaz, Berndt, Ashman: "Molecular cloning of cDNA encoding a novel platelet-endothelial cell tetra-span antigen, PETA-3." in: Blood, Vol. 86, Issue 4, pp. 1348-55, (1995) (PubMed).

  • 抗原
    CD151
    别名
    CD151 (CD151 产品)
    别名
    CD151 antibody, MGC83668 antibody, gp27 antibody, mer2 antibody, raph antibody, sfa1 antibody, peta-3 antibody, tspan24 antibody, PETA-3 antibody, SFA-1 antibody, Tspan24 antibody, GP27 antibody, MER2 antibody, RAPH antibody, SFA1 antibody, TSPAN24 antibody, CD151 molecule antibody, CD151 molecule (Raph blood group) L homeolog antibody, CD151 molecule (Raph blood group) antibody, CD151 antigen antibody, CD151 antibody, cd151.L antibody, cd151 antibody, Cd151 antibody
    背景
    Synonyms: PETA-3
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